Uterine Congenital Malformations

Question 1

Form the ..

• Vagina
• Cervix
• Uterus
• Fallopian tubes

Answer 1

Mullein ducts

Question 2

• Failure of formation
• Failure of fusion
• Failure of dissolation
• failure of disappearance

Answer 2

4 categories of Anomalous Genitalia

Question 3

▪ Complete agenesis- no vagina, CX, UT or tubes

▪ Partial agenesis- absence of CX and vaginal, or more common unicornuate UT and 1 fallopian tube

Answer 3

Failure of formation

Question 4

▪ Didelphys- 2 complete duplications(2 uteri, CX, and Vagina)
▪ Bicornuate UT- Single vaginal and CX but lack of fusion of upper uterine cavity (heart shaped)

Answer 4

Failure of fusion

Question 5

▪ Septate UT- single vagina and CX but uterine septum (endo)partially or completely separates into 2
**Appearance is most like a normal UT

Answer 5

Failure of dissolution

Question 6

▪ Failure of disappearance of structures that normally do not persist. M/C eg. Gartner Cyst (lateral vagina wall cyst resulting from remnants of Wolffian duct)

Answer 6

Failure of dissapearnce

Question 7

• Results of either mullein duct and or urogenital sinus malformation
• vaginal atresia, separations or duplications

Answer 7

Vagina Congenital malformation

Question 8

Endo and ovary respond to estrogen and progesterone levels in blood to

Answer 8

regulate hormones

Question 9

If estradiol levels decrease hypothalamus produces ______

Answer 9

GnRH & more

Question 10

GnRH(gonadotropin) comes from the ______

Answer 10

FSH - pituitary gland

Question 11

Hypothalamus comes from the ____

Answer 11

LH (pituitary)

Question 12

FSH produced in pituatry gives rise to produce

Answer 12

Estrogen which is in ovary

Question 13

LH in pituatry gives rise to produce

Answer 13

progesterone which is in corpus luteum

Question 14

• Stimulates growth & development of OV follicles
• follicles produce estrogen which stimulates endometrial growth
• As follicles from increase estradiol helps them to respond to LH and ovulation

Answer 14

FSH (follicle stimulating hormone)

Question 15

o Stimulates maturation and ovulation of Graafian follicle & subsequent corpus luteum formation
o LH stimulates progesterone production which peaks after ovulation
o If implantation occurs hCG production signals corpus luteum to continue progesterone secretion which prevents endo shedding
o If NO implantation progesterone ↓ & permits shedding of endo

Answer 15

LH (lutenizing hormone)