Urticaria Flashcards
What is urticaria?
also known as hives
small itchy lumps that appear on the skin
what can urticaria be associated with?
angioedema
flushing
patchy erythematous rash
What causes urticaria? what about acute vs chronic?
release of histamine by mast cells in the skin
acute - allergic
chronic - autoimmune
Causes of acute urticaria
allergies to food/meds/animals latex, chemicals viral infection insect bites dermatographism
dermatographism
rubbing of the skin
3 types of chronic urticaria
idiopathic
inducible
autoimmune
chronic idiopathic urticaria
recurrent episodes of chronic urticaria without a clear underlying cause or trigger
chronic inducible urticaria triggers
sunlight temp change exercise emotions pressure
autoimmune urticaria
eg SLE
main treatment for urticaria
antihistamines
antihistamine of choice for chronic urticaria
fexofenadine
what medications may be considered in a short course for severe flares?
oral steroids
specialist medications
anti-leukotrienes eg motelukast
omalizumab
cyclosporin