urinary pharm Flashcards
BCG vax
intravesical therapy
given weekly for 6-12 wk
moa: stim inflam response in bladder -> goal is for immune S to recognize cancerous cells and attack
live vaccine
BCG vax: SE
bladder irritation, systemic infection (esp in weakened immune bc live vax)
UTI type S
BCG vax: nc
pt instructions: empty bladder, instill BCG vax into bladder - like via I+O cath (dwell time 2 hr), change position q15 min (so med can touch all portions of bladder)
disinfect urine for 6 hr post treatment, watch for infection - bleach
trimethoprim/sulfamethoxazole
ciprofloxacin
ckd pharm
can be used to slow progression: reduce BP <140/90 (ace or arb, others prn), treat hld (chol <200, statin)
dont want to lower BP too fast bc kidneys used to high P and will not get perfused enough
treat complications: volume overload, hyperK, met acid, hyperP, renal osteodystrophy, anemai
complication of CDK: volume overload
loop diuretic (furosemide)
used with low salt diet
complication of CDK: hyperK
multiple
diuretic
addressed with hemodialysis in ESRD
complication of CDK: met acid
sodium bicarb
an alkaline agent - basic, will lower (raise?) pH
complication of CDK: hyperP
CaCO3
a phosphate binder
complication of CDK: renal osteodystrophy
calcitriol
activated vit D
complication of CDK: anemia
erythropoietin
black box! and how to use
sodium bicarb
for met acid, alkaline agent - basic so will lower (raise?) pH
goals: slow progression of ckd, prevent bone loss, improve nutrition
PO
initiate when HCO3 is <15 (goal = 18-20)
SE: safe, bloating
CaCO3
for hyperP
moa: bind P
goal: keep normal P levels, decrease mortality
take with meals
SE: hyperCa -> monitor levels
calcitrol
1, 25 dihydroxyvitamin D
for renal osteodystrophy
moa: activated form of vit D, stim intestinal abs of Ca/P and bone mineralization
SE: hyperCa, hyperP
