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Pharm Test 3 > Urinary Issues and Men's Health Issues (week 8&9) > Flashcards

Urinary Issues and Men's Health Issues (week 8&9) Flashcards

1
Q

Name a Cholinergic Muscarinic Agonist

A

Bethanechol (Urecholine)

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2
Q

What is Bethanechol (Urecholine) used for?

A

Urinary retention in post op, postpartum

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3
Q

What is the MOA of Bethanechol (Urecholine)?

A

Activates Muscarininc receptors of the urinary tract.

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4
Q

What are the adverse effects of Bethanchol (Urecholine)?

A

Hypotension
Bradycardia
Bronchoconstriction

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5
Q

Before administration of Bethanechol (Urecholine), what kind of PMH do you want to be aware of?

A

Hyperthyroidism
Hypotensive or Bradycardia pt’s
Small bowel or urinary tract obstructions

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6
Q

How should you administer Bethanechol (Urecholine)?

A

One hour before or after food

Nausea and vomiting will occur if taken with food

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7
Q

What is the reversal agent of Bethanechol (Urecholine)?

A

Atropine

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8
Q

What are the signs and symptoms of muscarinic poisoning?

A 
Profuse salivation and tearing
Bronchospasms
Diarrhea
Bradycardia
Hypotension
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9
Q

Name a Cholinergic M3 Antagonist

A

Oxybutynin (Ditropan XL)

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10
Q

What is Oxybutynin used for?

A

Overactive bladder

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11
Q

What is the MOA of Oxybutynin (Ditropan XL)?

A

Block M receptors of the urinary tract

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12
Q

What are some adverse effects of Oxybutynin (Ditropan XL)?

A

Meets Beers Criteria
Constipation, blurred vision, photophobia, dry eyes, and dry mouth
Tachycardia if blended into M1 and M2 receptors

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13
Q

What do you want to know before administering Oxybutynin (Ditropan XL)?

A

Urinary patterns

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14
Q

If someone has Glaucoma and severely decreased gastric motility, what drug can you not give them?

A

Oxybutynin (Ditropan XL)

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15
Q

What should you advise a patient to do when they are experiencing anticholinergic effects?

A

Chew gum
Wear sunglasses
Avoid hazardous activity

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16
Q

What is the reversal agent to Oxybutynin (ditropan XL) ?

A

Physostigmine

17
Q

What are the two major concerns for mens health?

A

Erectile Dysfunction

Benign Prostatic Hyperplasia

18
Q

What class of drugs are used to treat ED?

A

PDE5 Inhibitors

19
Q

Name two PDE5 Inhibitors

A

Sildenafil (Viagra)

Cialis

20
Q

What is the MOA of PDE5 Inhibitors?

A

Converst cGMP to GMP

21
Q

What is the MOA of Sildenafil (Viagra)?

A

Prevents cGMP from converting to GMP

22
Q

What is taken for Pulmonary arterial HTN but can also be used for ED?

A

Revatio

23
Q

When does Sildenafil (Viagra) peak?

A

60 min on an empty stomach of 2 hours after high fat meal

24
Q

What are some adverse effects of Sildenafil (Viagra)?

A

Hypotension in men taking Nitrates
Priapism (erection lasting over 6 hours)

Sudden hearing loss
Sudden vision loss

25
Q

When you should you take Viagra?

A

Once daily one hour before sexual activity

26
Q

What drug is given daily regardless of sexual activity?

A

Tadelafil (Cialis)

27
Q

What are the two approaches of BPH?

A

Mechanical (Overgrowth of epithelial cells)

Dynamic (Overgrowth of smooth muscle cells)

28
Q

Name a 5 -Alpha-Reductase Inhibitor

A

Finasteride (Proscar)

29
Q

What is Finasteride (Proscar) used for?

A

Enlarged prostate

30
Q

What is the MOA of Finasteride (Proscar)?

A

Promotes regression of prostate epithelial tissue

31
Q

Who should not take e Finasteride (Proscar)?

A

Pregnant women or those who may become pregnant

32
Q

If the PSA is constantly increasing, what does this indicate?

A

Prostate cancer

33
Q

Name an Alpha1-Adrenergic Antagonist

A

Tamsulosin (Flomax)

34
Q

What is Tamsulosin (Flomax) used for?

A

Mild prostatic enlargement but still having issues urinating

35
Q

What is the MOA of Tamsulosin (Flomax)?

A

Selective blockage of Alpha1 receptors relaxes smooth muscle in bladder neck and prostate

36
Q

What drug should be taken life long?

A

Tamsulosin (Flomax)

Pharm Test 3 (15 decks)

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