Antiemetics (week 8&9)

Question 1

What are antiemetics used for?

Answer 1

Given to suppress nausea and committing

Question 2

What do Serotonin Receptor Antagonists block?

Answer 2

Serotonin

5-HTs

Question 3

Name a Serotonin Antagonist

Answer 3

Ondansetron (Zofran)

Question 4

What is Ondansetron used for?

Answer 4

Chemotherapy
Radiation
Post Op

Question 5

What is an adverse effect of Ondansetron?

Answer 5

Prolonged QT intervals

Question 6

Name a Dopamine Antagonist

Answer 6

Prochlorperazine

Question 7

What is Prochlorperazine used for?

Answer 7

Chemotherapy

Post Op

Question 8

What do Dopamine Antagonists do?

Answer 8

Block dopamine receptors in the CTZ

Question 9

What are adverse reactions of Prochlorperazine?

Answer 9

Strong anti-cholinergic signs
Hypotension
Sedation
Tardive Dyskinesia

Question 10

Name a Cannabinoid

Answer 10

Dronabinol (Marinol)

Question 11

What is Dronabinal (Marinol) used for?

Answer 11

Chemotherapy

Question 12

Name a Anticholinergic

Answer 12

Scopolamine (Transderm Scop)

Question 13

What is Scopolamine (Transderm Scop) used for?

Answer 13

Motion Sickness

End of Life Care

Question 14

What is the MOA of Scopolamine (Transderm Scop)?

Answer 14

Blocks muscarinic receptors in the pathway from the inner ear to the vomiting center

Question 15

Name an Antihistamine

Answer 15

Dimenhydrinate

Question 16

What is Dimenhydrinate used for?

Answer 16

Motion sickness

Question 17

What is the MOA of Diphenhydrinate?

Answer 17

Blocks H1 receptors and muscarinic receptors in the pathway from the inner ear to the vomiting center