Anti-Protozoal Agents & Ectoparasiticides (week 10) Flashcards

1
Q

What are the three drugs for Antiprotozoal Agents and Ectoparasiticides?

A

Metronidazole
Permethrin
Malathion

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2
Q

Name an Antiprotozoal

A

Metronidazole (Flagyl)

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3
Q

What is Metronidazole (Flagyl) used for?

A

Intestinal amebiasis, amebic liver abscess

IV anaerobic infections

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4
Q

What is the MOA of Metronidazole (Flagyl)?

A

Disrupts DNA and protein synthesis

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5
Q

What are some common side effects for Metronidazole (Flagyl)?

A

Metallic taste

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6
Q

What are some serious side effects of Metronidazole (Flagyl)?

A

Seizures
Aseptic Meningitis
Encephalopathy
Steven-Johnsons Syndrome

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7
Q

What drug causes cimetidine, phenobarbital, phenytoin, lithium, and warfarin to be increased when taken at the same time?

A

Metronidazole

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8
Q

How is Metronidazole administered?

A

Topical - once a day
Oral -once a day
IV - infuse over 60 minutes

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9
Q

What are Ectoparasiticides used for?

A

Parasites that live on the surface of host

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10
Q

Scabies is caused by what?

A

Mites

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11
Q

Pediculosis is caused by what?

A

Lice

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12
Q

Where can Pediculosis be found?

A

Pubic area
Head
Body

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13
Q

What treatments are available for Ectoparasiticides?

A

Oral and Topical

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14
Q

Where do body lice reside at?

A

In clothing, move to the body to feed

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15
Q

What is the best treatment for Body lice?

A

Oral TMP/SMX

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16
Q

Public lice are shaped like what?

A

Crabs

17
Q

Phthirus pubis

A

Crabs

18
Q

Pediculosis ciliaris

A

Lice on the eyelashes

19
Q

What is the treatment for Pubic lice?

A

Permethrin and Malathion

20
Q

Irritation results from female mite burrowing beneath the skin to lay eggs; Burrows may be visible as small ridges or dotted lines

A

Scabies

21
Q

What are the primary symptoms of Scabies?

A

Pruritus; most intense just after going to bed

22
Q

What is the treatment for scabies?

A

Permethrin
Crtomiton
Malathion
Lindane

23
Q

What are the most common sites of scabies infestation?

A
Wrists
Elbows
Nipples
Navel
Genital Region 
Webs of the fingers
24
Q

What is Malathion used for?

A

Lice

25
Q

How do you administer Malathion?

A

Saturate dry hair
Allow to dry naturally with hair uncovered
After 8-12 hours, wash and rinse
Use a fine toothed comb to remove nits

26
Q

What is the trade name for Malathion?

A

Ovide

27
Q

What is the trade name for Permethrin?

A

Nix
Elimite
Acticin

28
Q

What is Permethrin used for?

A

Toxic to mites, lice and their ova

29
Q

How is Nix administered?

A

Apply to damp shampooed hair
Leave on 10 minutes and then rinse with warm water
Use fine-soothes comb to remove nits

30
Q

How is Elimite administered?

A

Massage into skin from head to soles of feet

Leave on 8-14 hours before washing