Anti-Protozoal Agents & Ectoparasiticides (week 10) Flashcards
What are the three drugs for Antiprotozoal Agents and Ectoparasiticides?
Metronidazole
Permethrin
Malathion
Name an Antiprotozoal
Metronidazole (Flagyl)
What is Metronidazole (Flagyl) used for?
Intestinal amebiasis, amebic liver abscess
IV anaerobic infections
What is the MOA of Metronidazole (Flagyl)?
Disrupts DNA and protein synthesis
What are some common side effects for Metronidazole (Flagyl)?
Metallic taste
What are some serious side effects of Metronidazole (Flagyl)?
Seizures
Aseptic Meningitis
Encephalopathy
Steven-Johnsons Syndrome
What drug causes cimetidine, phenobarbital, phenytoin, lithium, and warfarin to be increased when taken at the same time?
Metronidazole
How is Metronidazole administered?
Topical - once a day
Oral -once a day
IV - infuse over 60 minutes
What are Ectoparasiticides used for?
Parasites that live on the surface of host
Scabies is caused by what?
Mites
Pediculosis is caused by what?
Lice
Where can Pediculosis be found?
Pubic area
Head
Body
What treatments are available for Ectoparasiticides?
Oral and Topical
Where do body lice reside at?
In clothing, move to the body to feed
What is the best treatment for Body lice?
Oral TMP/SMX
Public lice are shaped like what?
Crabs
Phthirus pubis
Crabs
Pediculosis ciliaris
Lice on the eyelashes
What is the treatment for Pubic lice?
Permethrin and Malathion
Irritation results from female mite burrowing beneath the skin to lay eggs; Burrows may be visible as small ridges or dotted lines
Scabies
What are the primary symptoms of Scabies?
Pruritus; most intense just after going to bed
What is the treatment for scabies?
Permethrin
Crtomiton
Malathion
Lindane
What are the most common sites of scabies infestation?
Wrists Elbows Nipples Navel Genital Region Webs of the fingers
What is Malathion used for?
Lice
How do you administer Malathion?
Saturate dry hair
Allow to dry naturally with hair uncovered
After 8-12 hours, wash and rinse
Use a fine toothed comb to remove nits
What is the trade name for Malathion?
Ovide
What is the trade name for Permethrin?
Nix
Elimite
Acticin
What is Permethrin used for?
Toxic to mites, lice and their ova
How is Nix administered?
Apply to damp shampooed hair
Leave on 10 minutes and then rinse with warm water
Use fine-soothes comb to remove nits
How is Elimite administered?
Massage into skin from head to soles of feet
Leave on 8-14 hours before washing
