Urinary Flashcards

1
Q

What is the normal pH of urine?

A

7.5-8.5

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2
Q

What urinary biochemical can be used to identify proximal tubular necrosis?

A

GGT

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3
Q

Which Leptopsira has been assocaited with anaemia and haemoglobinuria

A

L. iterrogans Pomona

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4
Q

Which virus (also assocaited with respiratory dz) has been a rarely reported cause of cortical interstitial nephritis?

A

Adenovirus

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5
Q

Describe the pathology seen with lamb nephrosis

A

Large, pale, soft kidneys. Protein losing nephropathy. Hyalin casts. Focal glomerular necrosis.

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6
Q

List 5 broad categories of renal toxins

A

Oxalates
Tannins
Heavy metals
Vitamin D
Ethylene glycol

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7
Q

List 4 oxalate containing plants

A

Dock, sorrel, beet leaves, rhubarb

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8
Q

List two plants with toxic levels of vitamin D

A

Jasmine, nightshades

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9
Q

List six heavy metals associated with renal toxicity

A

Copper, Zinc, Lead, Mercury, Cadmium, Arsenic

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10
Q

Give a ballpark figure for toxic copper dose in sheep (much variation)

A

20ppm

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11
Q

What copper:molybdenum ratio is reported as high risk for toxicity

A

> 10:1

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12
Q

Explain the pathophysiology of copper toxicity

A

Excess copper is stored in the lysosomes of the liver. It is acutely released during stress. This oxidises haemoglobin to methaemoglobin. Oxidative stress triggers red blood cell lysis.

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13
Q

In which kidney is pyelonephritis more common?

A

Left (shorter ureter)

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14
Q

What bacteria is the most common cause of pyelonephritis? How does urinary acidification help to treat?

A

Corynebacterium renale. Acidification prevents pili adhering

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15
Q

What are the two generak causes of renal amyloidosis

A

Chronic inflammation (amyloid A), myeloma (amyloid L)

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16
Q

In which breed is there an inherited mesangiocapillary glomerulonephritis?

A

Finnish Landrace

17
Q

In which breed of goat has Cloisonnè kidney been reported? What is the pathogenesis?

A

Angora goats. Repeated intravascular haemolysis leads to thickened, brown basement membrane.

18
Q

What is the genetic inheritance mode of polycystic renal disease?

A

Autosomal recessive

19
Q

Lesions in which spinal cord segments cause a distended bladder that is difficult to express?

A

UMN: L4-S2

20
Q

Lesions in which spinal cord segments cause a distended bladder that is easy to express and may spontaneously dribble?

A

LMN: S2-caudal

21
Q

List three causes of neurological incontinence

A

Swayback. High tail docking. West Nile Virus.

22
Q

Deficiency of which vitamin may predispose to urolothiasis via metaplasia of the uroepithelium?

A

Vitmain A

23
Q

Which uroliths are most commonly seen in animals on a high grain diet?

A

Struvite and Apatite

24
Q

Which plant family is associated with calcium carbonate uroliths?

A

legumes

25
Q

Why may serum phosphorous and potassium be normal in cases of obstructive urolithiasis

A

Increased salivary excretion

26
Q

List the five surgical options for urolithiasis

A

Urethrotomy, urethrostomy, tube cystotomy, marsupialisation, penile amputation

27
Q

What is the prognosis for tube cystotomy? Within what time should you expect urination?

A

70%. Within 14 days

28
Q

List risk factors for urolithiasis

A

Early castration. Excessive P/Ca. Insufficient chewing (not enough long fibre, too much grain). Slug-feeding (osmotic draw of water into rumen increases urine concentration)

29
Q

Which pathogens are assocaited with Pizzle Rot (Ulcerative posthitis and vaginitis)

A

Corynbacterium renale.
Less so: parapox, C. pilosum, C. cytidis, CHV-1, mycoplasmas, ureaplasmas

30
Q

List risk factors for pizzle rot

A

High protein diets, thick fleece near genitals, wet conditions, increased lying (e.g. lameness)

31
Q
A