Unit 6 Flashcards
Antacids MOA:
neutralizes gastric acidity
Antacids Adverse Effects:
diarrhea, constipation, kidney stones
Antacids Indications:
heartburn
Antacids Contraindications:
drug allergy, renal failure, electrolyte disturbance
Famotidine (H2 Receptor Antagonist) MOA:
blocks H2 receptor of acid-producing parietal cells
Famotidine (H2 Receptor Antagonist) Adverse Effects:
diarrhea, nausea, abdominal cramps, headache
Famotidine (H2 Receptor Antagonist) Indications:
GERD, peptic ulcer disease
Famotidine (H2 Receptor Antagonist) Contraindications:
drug allergy, kidney & liver dysfunction
Omeprazole (proton pump inhibitor) MOA:
blocks gastric acid secretion
Omeprazole (proton pump inhibitor) Adverse Effects:
well tolerated
Omeprazole (proton pump inhibitor) Indications:
erosive esophagitis, GERD
Omeprazole (proton pump inhibitor) Contraindications:
drug allergy
Sucralfate (misc. acid controlling drug) MOA:
mucosal protectant
Sucralfate (misc. acid controlling drug) Adverse Effects:
nausea, constipation, and dry mouth
Sucralfate (misc. acid controlling drug) Indications:
stress ulcerations
Sucralfate (misc. acid controlling drug) Contraindications:
drug allergy
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) MOA:
inhibits GI motility and GI propulsion
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) Adverse Effects:
drowsiness, urinary retention, dizziness
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) Indications:
diarrhea
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) Contraindications:
drug allergy, GI blockage
Senna
Lactulose: reduces serum ammonia levels (Laxative) MOA:
promote bowel movements
Senna
Lactulose: reduces serum ammonia levels (Laxative) Adverse Effects:
skin rashes, gastric irritation, electrolyte imbalance
Senna
Lactulose: reduces serum ammonia levels (Laxative) Indications:
constipation
Senna
Lactulose: reduces serum ammonia levels (Laxative) Contraindications:
drug allergy, fecal impaction
Meclizine (Antihistamines) MOA:
blocks one of the vomiting passageways
Meclizine (Antihistamines) Adverse Effects:
dizziness, drowsiness
Meclizine (Antihistamines) Indications:
nausea, vomiting
Meclizine (Antihistamines) Contraindications:
drug allergy
Metoclopramide (Prokinetics) MOA:
block one of the vomiting passageways
Metoclopramide (Prokinetics) Adverse Effects:
hypotension, sedation, restlessness
Metoclopramide (Prokinetics) Indications:
nausea/vomiting
Metoclopramide (Prokinetics) Contraindications:
drug allergy
Ondansetron (Serotonin Blockers) MOA:
blocks one of the vomiting passageways
Ondansetron (Serotonin Blockers) Adverse Effects:
headache, diarrhea, rash
Ondansetron (Serotonin Blockers) Indications:
nausea, vomiting
Ondansetron (Serotonin Blockers) Contraindications:
drug allergy
Ascorbic Acid (vitamin C) [Water soluble vitamins] MOA:
reversibly oxidized to dehydroascorbic acid and acts in oxidation-reduction reactions
Ascorbic Acid (vitamin C) [Water soluble vitamins] Adverse Effects:
nausea, vomiting, headache and abdominal cramps