Unit 6 Flashcards
Antacids MOA:
neutralizes gastric acidity
Antacids Adverse Effects:
diarrhea, constipation, kidney stones
Antacids Indications:
heartburn
Antacids Contraindications:
drug allergy, renal failure, electrolyte disturbance
Famotidine (H2 Receptor Antagonist) MOA:
blocks H2 receptor of acid-producing parietal cells
Famotidine (H2 Receptor Antagonist) Adverse Effects:
diarrhea, nausea, abdominal cramps, headache
Famotidine (H2 Receptor Antagonist) Indications:
GERD, peptic ulcer disease
Famotidine (H2 Receptor Antagonist) Contraindications:
drug allergy, kidney & liver dysfunction
Omeprazole (proton pump inhibitor) MOA:
blocks gastric acid secretion
Omeprazole (proton pump inhibitor) Adverse Effects:
well tolerated
Omeprazole (proton pump inhibitor) Indications:
erosive esophagitis, GERD
Omeprazole (proton pump inhibitor) Contraindications:
drug allergy
Sucralfate (misc. acid controlling drug) MOA:
mucosal protectant
Sucralfate (misc. acid controlling drug) Adverse Effects:
nausea, constipation, and dry mouth
Sucralfate (misc. acid controlling drug) Indications:
stress ulcerations
Sucralfate (misc. acid controlling drug) Contraindications:
drug allergy
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) MOA:
inhibits GI motility and GI propulsion
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) Adverse Effects:
drowsiness, urinary retention, dizziness
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) Indications:
diarrhea
Diphenoxylate with atropine loperamide (Anti-diarrheal/Opioid) Contraindications:
drug allergy, GI blockage
Senna
Lactulose: reduces serum ammonia levels (Laxative) MOA:
promote bowel movements
Senna
Lactulose: reduces serum ammonia levels (Laxative) Adverse Effects:
skin rashes, gastric irritation, electrolyte imbalance
Senna
Lactulose: reduces serum ammonia levels (Laxative) Indications:
constipation
Senna
Lactulose: reduces serum ammonia levels (Laxative) Contraindications:
drug allergy, fecal impaction
Meclizine (Antihistamines) MOA:
blocks one of the vomiting passageways
Meclizine (Antihistamines) Adverse Effects:
dizziness, drowsiness
Meclizine (Antihistamines) Indications:
nausea, vomiting
Meclizine (Antihistamines) Contraindications:
drug allergy
Metoclopramide (Prokinetics) MOA:
block one of the vomiting passageways
Metoclopramide (Prokinetics) Adverse Effects:
hypotension, sedation, restlessness
Metoclopramide (Prokinetics) Indications:
nausea/vomiting
Metoclopramide (Prokinetics) Contraindications:
drug allergy
Ondansetron (Serotonin Blockers) MOA:
blocks one of the vomiting passageways
Ondansetron (Serotonin Blockers) Adverse Effects:
headache, diarrhea, rash
Ondansetron (Serotonin Blockers) Indications:
nausea, vomiting
Ondansetron (Serotonin Blockers) Contraindications:
drug allergy
Ascorbic Acid (vitamin C) [Water soluble vitamins] MOA:
reversibly oxidized to dehydroascorbic acid and acts in oxidation-reduction reactions
Ascorbic Acid (vitamin C) [Water soluble vitamins] Adverse Effects:
nausea, vomiting, headache and abdominal cramps
Ascorbic Acid (vitamin C) [Water soluble vitamins] Indications:
vitamin c deficiency, dietary supplement
Ascorbic Acid (vitamin C) [Water soluble vitamins] Contraindications:
drug allergy
Calcium (Mineral) MOA:
building blocks for body structures
Calcium (Mineral) Adverse Effects:
hypercalcemia, anorexia, constipation
Calcium (Mineral) Indications:
low calcium levels
Calcium (Mineral) Contraindications:
hypercalcemia, dysrhythmias, drug allergy
Vitamin K (Fat soluble vitamin) MOA:
effective blood clotting
Vitamin K (Fat soluble vitamin) Adverse Effects:
headache, rash, nausea, urticaria
Vitamin K (Fat soluble vitamin) Indications:
dietary supplement & treats deficiency
Vitamin K (Fat soluble vitamin) Contraindications:
drug allergy
Epoetin Alfa (Erythropoiesis- Stimulating Drugs) MOA:
stimulates the red blood cell progenitor cells in the bone marrow
Epoetin Alfa (Erythropoiesis- Stimulating Drugs) Adverse Effects:
????
Epoetin Alfa (Erythropoiesis- Stimulating Drugs) Indications:
anemia
Epoetin Alfa (Erythropoiesis- Stimulating Drugs) Contraindications:
drug allergy, hypertension
What does Epoetin Alfa require to work?
adequate iron stores in the body
Ferrous Sulfate (Iron) MOA:
oxygen carrier in both hemoglobin and myoglobin and is critical for tissue respiration
Ferrous Sulfate (Iron) Adverse Effects:
nausea, vomiting, stomach cramps
Ferrous Sulfate (Iron) Indications:
supplements and iron-deficiency anemia
Ferrous Sulfate (Iron) Contraindications:
drug allergy, hemolytic anemia
Folic Acid (Water soluble B-complex vitamin) MOA:
erythropoiesis and synthesis of DNA and RNA
Folic Acid (Water soluble B-complex vitamin) Adverse Effects:
allergic reaction and yellow discoloration in urine
Folic Acid (Water soluble B-complex vitamin) Indications:
folic acid deficiency
Folic Acid (Water soluble B-complex vitamin) Contraindications:
drug allergy
Enteral Nutrition:
- Administered through the mouth or feeding tube
- NG tube
- PEG(percutaneous endoscopic gastrostomy) Tube
Parental Nutrition:
- Administered through IV
- Requires a central line
- Used after enteral therapy fails
- Hypertonic solution
- Monitor blood sugar, and electrolytes
Bacitracin (Antimicrobials) MOA:
inhibits bacterial wall synthesis
Bacitracin (Antimicrobials) Adverse Effects:
skin rash, anaphylactoid: itching, burning and inflammation
Bacitracin (Antimicrobials) Indications:
skin infections
Bacitracin (Antimicrobials) Contraindications:
drug allergy
Benzoyl Peroxide (Anti acne) MOA:
continuously liberates active oxygen in the skin
Benzoyl Peroxide (Anti acne) Adverse Effects:
related to dose: peeling of skin, redness, sensation of warmth
Benzoyl Peroxide (Anti acne) Indications:
acne
Benzoyl Peroxide (Anti acne) Contraindications:
drug allergy
Clotrimazole (Anti fungal) MOA:
control fungal infections
Clotrimazole (Anti fungal) Adverse Effects:
local irritation, pruritus, burning sensation, and scaling
Clotrimazole (Anti fungal) Indications:
fungal infection
Clotrimazole (Anti fungal) Contraindications:
????
Pilocarpine [Cholinergics (Miotics)] MOA:
allows for changes of the eye
Pilocarpine [Cholinergics (Miotics)] Adverse Effects:
blurred vision
Pilocarpine [Cholinergics (Miotics)] Indications:
open angle glaucoma
Pilocarpine [Cholinergics (Miotics)] Contraindications:
drug allergy
Timolol (Beta- Adrenergic Blockers) MOA:
reduce elevated and normal intraocular pressure
Timolol (Beta- Adrenergic Blockers) Adverse Effects:
blurred vision, pain, photophobia
Timolol (Beta- Adrenergic Blockers) Indications:
elevated intraocular pressure
Timolol (Beta- Adrenergic Blockers) Contraindications:
drug allergy
Gentamicin (Antimicrobial) MOA:
destroy the invading organism
Gentamicin (Antimicrobial) Adverse Effect:
burning and stinging
Gentamicin (Antimicrobial) Indications:
infection
Gentamicin (Antimicrobial) Contraindications:
drug allergy
Tetracaine (Topical Anesthetics) MOA:
stabilize the membranes of nerves, which results in a decrease in the movement of ions into and out of the nerve endings
Tetracaine (Topical Anesthetics) Adverse Effects:
stinging, burning, redness, and lacrimation
Tetracaine (Topical Anesthetics) Indications:
pain
Tetracaine (Topical Anesthetics) Contraindications:
drug allergy
Carbamide peroxide (Earwax Emulsifiers) MOA:
softens and lubricates ear wax
Carbamide peroxide (Earwax Emulsifiers) Adverse Effects:
none
Carbamide peroxide (Earwax Emulsifiers) Indications:
earwax
Carbamide peroxide (Earwax Emulsifiers) Contraindications:
drug allergy