Chapter 27

Question 1

Simvastatin, atorvastatin (statins)

Answer 1

• MOA: lowers blood cholesterol by decreasing the production of cholesterol
• Adverse effects: abdominal pain, rash, or headache rhabdomyolysis
• Indications: hypercholesterolemia
• Contraindications: drug allergy and pregnancy

Question 2

Furosemide (loop diuretics)

Answer 2

• MOA: works in the loop of Henle by blocking chloride and sodium resorption
• Adverse effects: dizziness, headache, hypokalemia
• Indications: manage edema
• Contraindications: drug allergy, hepatic coma, and electrolyte loss

Question 3

Sprinolactone (potassium sparing diuretic)

Answer 3

• MOA: blocks resorption of sodium
• Adverse effects: dizziness, headache, cramps
• Indications: hypertension
• Contraindications: drug allergy, kyperkalemia, renal failure

Question 4

Hydrochlorothiazide (thiazide)

Answer 4

• MOA: inhibit resorption of sodium, potassium, and chloride
• Adverse effects: dizziness, headache, hypokalemia
• Indications: edema
• Contraindications: drug allergy

Question 5

Potassium

Answer 5

• MOA: intracellular electrolyte
• Adverse effects: diarrhea, nausea, and vomiting
• Indications: potassium depletion
• Contraindications: drug allergy, hyperkalemia

Question 6

Sodium

Answer 6

• MOA: major cation in the extracellular fluid, regulates fluid distribution
• Adverse effects: nausea, vomiting, and cramps
• Indications: sodium depletion
• Contraindications: drug allergy, hypernatremia