Chapter 22

Question 1

Clonidine (Adrenergic)

Answer 1

• MOA: Alpha 2 ; vasodilation to decrease blood pressure
• Adverse Effects: bradycardia w/ reflex tachycardia, postural hypotension, dizziness and sexual dysfunction
• Contraindication: drug allergy & heart failure

Question 2

Captopril (ACE)

Answer 2

• MOA: inhibits angiotensin 1 to convert angiotensin 2
• Adverse effects: dizziness, fatigue, headache, non productive cough
• Contraindications: drug allergy, angioedema, lactation women
• Indication: Hypertension and to reduce cardiovascular disease

Question 3

Hydralzine (Vasodilator)

Answer 3

• MOA: causes peripheral vasodilation
• Adverse effects: dizziness, headache, tachycardia, dyspnea
• Contraindications: drug allergy, hypotension, head injury, and MI

Question 4

Losartan (Angiotensin II Receptor Blocker)

Answer 4

• MOA: block the binding of AII to type 1 AII receptors
• Adverse effects: chest pain, fatigue, hypoglycaemia
• Contraindications: drug allergy, pregnancy, and lactation