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Pharmacology > Unit 4 > Flashcards

Unit 4 Flashcards

1
Q

Somatropin (Growth Hormone) MOA:

A

enhance growth

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2
Q

Somatropin (Growth Hormone) Adverse Effects:

A

headache, hyperglycemia, rash, flulike syndrome

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3
Q

Somatropin (Growth Hormone) Indications:

A

treatment of growth failure

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4
Q

Somatropin (Growth Hormone) Contraindications:

A

drug allergy, acute illness and children w/ closed growth plates

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5
Q

Vasopressin MOA:

A

enhances antidiuretic hormone

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6
Q

Vasopressin Adverse Effects:

A

hypertension, vertigo, headache

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7
Q

Vasopressin Indications:

A

diabetes insipidus

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8
Q

Vasopressin Contraindications:

A

drug allergy, asthma, cardiovascular disease

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9
Q

Levothyroxine MOA:

A

induces changes in the metabolic rate

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10
Q

Levothyroxine Adverse Effect:

A

cardiac dysrhythmia

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11
Q

Levothyroxine Indications:

A

hypothyroidism

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12
Q

Levothyroxine Contraindications:

A

drug allergy, hyperthyroidism, and MI (!)

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13
Q

Propylthiouracil MOA:

A

inhibit the incorporation of iodine molecules into amino acid tyrosine`

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14
Q

Propylthiouracil Adverse Effect:

A

liver and bone marrow toxicity

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15
Q

Propylthiouracil Indications:

A

hyperthyroidism

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16
Q

Propylthiouracil Contraindications:

A

drug allergy

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17
Q

Nursing diagnosis for thyroid & antithyroid medications:

A

The nursing dx for Levothyroxine and Propylthiouracil is knowledge deficit AND noncompliance

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18
Q

The 3P’s of Diabetes:

A

Polyphagia, polyuria, polydipsia

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19
Q

Route of Rapid-Acting Insulin:

A

Subcutaneous

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20
Q

Onset of RAI:

A

15 minutes

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21
Q

Peak and Duration of RAI:

A

Peaks in 1-2 hours

Duration of 3-5 hours

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22
Q

Half-life of RAI:

A

80 min

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23
Q

Route Short Acting Insulin:

A

Subcutaneous and Intravenous !

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24
Q

Onset of SAI:

A

30-60 minutes

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25
Q

Peak and Duration of SAI:

A

Peak is 2.5 hours

Duration is 6-10 hours

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26
Q

Half-life of SAI:

A

Unknown

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27
Q

Glipizide MOA:

A

stimulate release of insulin

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28
Q

Glipizide Adverse Effects:

A

hypoglycemia & weight gain

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29
Q

Glipizide Indications:

A

Type 2 Diabetes (hyperglycemia)

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30
Q

Glipizide Contraindications:

A

Hypoglycemia, drug allergy

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31
Q

Metformin MOA:

A

decrease glucose production by the liver

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32
Q

Metformin Adverse Effects:

A

GI Symptoms: abdominal bloating and diarrhea

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33
Q

Metformin Indications:

A

Type 2 Diabetes

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34
Q

Metformin Contraindications:

A

renal disease & drug allergy

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35
Q

Fludocortisone (mineralcorticoid) MOA:

A

modify enzyme activity

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36
Q

Fludocortisone (mineralcorticoid) Adverse Effects:

A

hypertension, convulsions, weight gain, and hyperglycemia

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37
Q

Fludocortisone (mineralcorticoid) Indications:

A

Adrenocortical insufficiency

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38
Q

Fludocortisone (mineralcorticoid) Contraindications:

A

drug allergy

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39
Q

Methylprednisone (glucocorticoid) MOA:

A

modify enzyme activity

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40
Q

Methylprednisone (glucocorticoid)
Adverse Effect:

A

hypertension, convulsions, weight gain, and hyperglycemia

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41
Q

Methylprednisone (glucocorticoid)
Indications:

A

chronic respiratory illness

42
Q

Methylprednisone (glucocorticoid)
Contraindications:

A

drug allergy

43
Q

Alendronate MOA:

A

inhibits or reverses osteoclast-mediated bone resportion

44
Q

Aldendronate must be taken…

A

with 8 oz of water first thing in the morning

45
Q

Aldendronate Adverse Effects:

A

GI upset

46
Q

Aldendronate Indications:

A

osteoporosis

47
Q

Aldendronate Contraindications:

A

drug allergy, dysphagia, esophagitis

48
Q

Calcitonin (Bisphosphonates) MOA:

A

inhibits osteoclastic bone resportion

49
Q

Calcitonin (Bisphosphonates) Adverse Effects:

A

nausea and vomiting

50
Q

Calcitonin (Bisphosphonates) Indications:

A

osteoporosis

51
Q

Calcitonin (Bisphosphonates) Contraindications:

A

drug allergy & salmon

52
Q

Clomiphene (fertility rx) MOA:

A

blocking estrogen receptors in the uterus and the brain

53
Q

Clomiphene (fertility rx) Adverse Effect:

A

tachycardia, dizziness, bloating, multiple pregnancies

54
Q

Clomiphene (fertility rx) Indications:

A

promote ovulation

55
Q

Clomiphene (fertility rx) Contraindications:

A

drug allergy and ovarian failure

56
Q

Oxytocin MOA:

A

stimulates uterine contraction

57
Q

Oxytocin Adverse Effects:

A

hypo/hypertension, chest pain, cramping

58
Q

Oxytocin Indications:

A

induce labor

59
Q

Oxytocin Contraindications:

A

drug allergy & high risk intrauterine positions

60
Q

Contraceptive Rx MOA:

A

prevent ovulation by inhibiting the release of gonadotropins and increasing uterine mucous viscosity

61
Q

Contraceptive Rx Adverse Effects:

A

hypertension, edema, migraines, increased weight, amenorrhea and breast changes

62
Q

Contraceptive Rx Indications:

A

prevention of pregnancy

63
Q

Contraceptive Rx Contraindications:

A

pregnancy, MI, stroke, pulmonary embolism

64
Q

Finasteride MOA:

A

prevents the conversion of testosterone DHT

65
Q

Finasteride Adverse Effects:

A

reduced libido, hypotension, dizziness, and drowsiness

66
Q

Finasteride Indications:

A

benign prostatic hyperplasia

67
Q

Finasteride Contraindcations:

A

drug allergy, pregnant women and children

68
Q

Sidenafil (Viagra) MOA:

A

inhibits action of the enzyme phosphodiesterase

69
Q

Sidenafil (Viagra) Adverse Effect:

A

hypotension, headache, flushing

70
Q

Sidenafil (Viagra) Indications:

A

ED

71
Q

Sidenafil (Viagra) Contraindications:

A

cardiovascular disease, drug allergy, nitrates

72
Q

Testosterone MOA:

A

stimulates normal growth & development of secondary sex characteristics

73
Q

Diphenyhydromine; Ioratadine (antihistamine) MOA:

A

blocks histamine receptors

74
Q

Diphenyhydromine; Ioratadine (antihistamine) Adverse:

A

drowsiness, dry mouth, vision changes

75
Q

Diphenyhydromine; Ioratadine (antihistamine) Indications:

A

nasal allergies, allergic rhinitis, uticaria

76
Q

Diphenyhydromine; Ioratadine (antihistamine) Contraindications:

A

drug allergy

77
Q

Benzonatate; Dextromethorphan (Antitussive) MOA:

A

Benzonatate: numbs stretch receptor cells in respiratory tract

Dextromethorphan: suppresses cough center

78
Q

Benzonatate; Dextromethorphan (Antitussive) Adverse:

A

Benzonatate: dizziness, headache, sedation

Dextromethrophan: dizziness, drowsiness, nausea

79
Q

Benzonatate; Dextromethorphan (Antitussive) Indications:

A

cough

80
Q

Benzonatate; Dextromethorphan (Antitussive) Contraindications:

A

drug allergy

81
Q

Codeine (antitussive) MOA:

A

suppresses cough through direct action on cough center

82
Q

Codeine (antitussive) Adverse Effects:

A

sedation, light-headedness, constipation

83
Q

Codeine (antitussive) Indications:

A

cough

84
Q

Codeine (antitussive) Contraindications:

A

drug allergy

85
Q

Guaifenesin (expectorant) MOA:

A

loosening & thinning respiratory secretions

86
Q

Guaifenesin (expectorant) Adverse Effects:

A

gastric irritation

87
Q

Guaifenesin (expectorant) Indications:

A

relief of productive cough

88
Q

Guaifenesin (expectorant) Contraindications:

A

drug allergy

89
Q

Albuterol (bronchodilator);

Ipratroprium-anticholinergic (Beta-adrenergic agonist);

Salmeterol (Sympathomimetic)

MOA:

A

relax and dilate airways

90
Q

Albuterol (bronchodilator);

Ipratroprium-anticholinergic (Beta-adrenergic agonist);

Salmeterol (Sympathomimetic)

Adverse Effects:

A

restlessness, cardiac stimulation, hyperglycemia

91
Q

Albuterol (bronchodilator);

Ipratroprium-anticholinergic (Beta-adrenergic agonist);

Salmeterol (Sympathomimetic)

Indications:

A

prevent bronchospasms

92
Q

Albuterol (bronchodilator);

Ipratroprium-anticholinergic (Beta-adrenergic agonist);

Salmeterol (Sympathomimetic)

Contraindications:

A

drug allergy, hypertension, cardiac dysrhythmias

93
Q

Montelukast (Leukotriene Receptor Antagonist) MOA:

A

blocks the inflammatory process with asthma

94
Q

Montelukast (Leukotriene Receptor Antagonist) Adverse Effects:

A

headache, dizziness, and insomnia

95
Q

Montelukast (Leukotriene Receptor Antagonist) Indications:

A

prophylaxis and long term treatment of asthma

96
Q

Montelukast (Leukotriene Receptor Antagonist) Contraindications:

A

drug allergy

97
Q

Fluticasone Propionate; Methylprednisolone (selected corticosteroids) MOA:

A

reducing inflammation and enhancing beta agonist

98
Q

Fluticasone Propionate; Methylprednisolone (selected corticosteroids) Adverse Effects:

A

CNS effects, prone to infections, dermatologic issues

99
Q

Fluticasone Propionate; Methylprednisolone (selected corticosteroids) Indications:

A

Fluticasone Propionate: asthma prophylaxis and maintenance

Methylprednisolone: exacerbation of asthma & COPD

100
Q

Fluticasone Propionate; Methylprednisolone (selected corticosteroids) Contraindications:

A

drug allergy

Pharmacology (20 decks)

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