UNIT 3: Viruses Flashcards
Virology
The study of viruses
Basic structure of viruses
All viruses are composed of an outer protein coat (capsid) surrounding a piece of DNA or RNA. They do not possess both types of nucleic acid.
Rod-shaped viruses
- viruses that are rod-shaped have proteins packaged tightly into a helix e.g. tobacco mosaic virus
Round shaped virus
Viruses that are round are composed of 20 identical proteins arranged into a Spherical protein coat e.g. rhinovirus which causes colds and flu
Complex shaped viruses
Comprise a large group of viruses with shapes that vary widely. The most common shape is that of the bacteriophage -that infect bacterial cells.
Obligate parasites
They can only replicate using a living cells
Replication of viruses: attachment
The virus uses its external proteins to latch onto a target cell
Replication of viruses: entry
Either the entire virus enters the cell or it injects its nucleic acid into the cell
Replication of viruses: replication
The virus or the viral nucleic acid takes over the cells nucleus and protein synthesis system (ribosome). New viral proteins are synthesised and new copies of viral DNA/RNA are also synthesised
Replication of viruses: assembly
The new DNA/RNA and viral proteins are assembled in their correct positions to make new viruses.
Replication of viruses: release
The newly formed viral particles are released from the cell either by budding out through the cell membrane or by causing the cell to burst
Beneficial effects of viruses
- viruses are regularly used in genetic engineering of various types of cells. They are used as vectors.
- it is hoped that bacteriophage viruses may in the future be used to treat serious bacterial infections in humans, eventually replacing antibiotics
Harmful effects of viruses
- viruses can cause illness and disease: for example in humans viruses cause colds and influenza (rhinovirus), AIDS (HIV), hepatitis, poliomyelitis, measles and chicken pox. And in other organisms conditions such as foot and mouth disease in ruminants and various mosaic diseases in plants ( tobacco mosaic virus in the tobacco plant)
Bacteriophage
A virus that infects bacteria