UNIT 2: The cell cycle Flashcards
cell continuity
cells that arise from cells of the same type.
living organisms maintain cell continuity by mitosis and cell division
chromatin
elongated DNA
chromosomes
composed of DNA and protein.
arranged into homologous pairs - pairs of chromosomes that contain genes that control the same characteristics.
haploid
one set of chromosomes
in humans, the haploid number is 23
diploid
2 sets of chromosomes
in humans the diploid number is 46 - arranged into 23 pairs
the cell cycle
The changes that take place in a cell during the period between one cell division and the next. occurs under three distinct stages: 1. interphase 2. mitosis 3. cell division
interphase
- the stage where a cell is not dividing and a cell spends the vast majority of its time in this stage.
- chromosomes are elongated and the cell goes about its daily functions.
- towards the end of interphase the cell organelles and DNA are replicated.
end of interphase
the DNA is replicated and condenses into duplicated chromosomes which are held together by centrometres.
mitosis
the nuclear division in which one nucleus divides to form 2nuclei, each containing the same number of chromosomes with identical genes. stage 1: prophase stage 2: metaphase stage 3: anaphase stage 4: telophase
prophase
the nuclear membrane begins to disappear and spindle fibres begin to appear from the centrioles.
metaphase
the replicated chromosomes line up along the equator of the cell held in place by spindle fibres.
anaphase
the spindle fibres begin to contract pulling one chromosome from each pair to each pole.
telophase
the chromosomes at each pole begin to unravel and lengthen, spindle fibres disappear, and nuclear membranes reform at each pole.
cell division (cytokinesis)
cell division occurs immediately after mitosis and involves formation of cleavage furrow (in animal cells) or cell plate (in plant cells) prior to cell splitting
cell division - meiosis
meiosis is nuclear division in which the four daughter nuclei contain half the chromosomes number of the parent nucleus
cancer
a disease whereby a cell loses its ability to control both the rate of mitosis and cell division.
- mitosis is normally carefully controlled but when it is out of control it can result in cancer.
- benign cancer involves cells that divide out of control for a limited period of time and do not spread.
- malignant cancer involves cells that divide rapidly uncontrollably and spread and invade other tissues - destroying that tissue in the process.
- anything that has the potential to cause cancer = carcinogen - destroys DNA
-
carcinogens
UV light- damages DNA of skin cells
cigarette smoke - damages the DNA of cells lining the mouth, airways and lungs.
Gene
A section of DNA that contains the instructions for the formation of a protein
Centromere
A point at which the chromosomes are attached in a double stranded chromosome