Unit 2 - Transport - Feb 24 Flashcards
Diffusion
when small mostly-nonpolar molecules and very small polar molecules (e.g., water) can pass directly through the membrane (high->low concentration)
Osmosis
movement of water across a semipermeable membrane (toward higher solute concentration - can defy gravity)
Hypertonic, Isotonic, Hypotonic solution
Hypertonic: high in solute
Isotonic: equal in solute and water
Hypotonic: low in solute
-Very Hypotonic: blood cell would burst
Integral Membrane Proteins
amphipathic proteins that can integrate into the lipid bilayer
Transmembrane domains
usually contain hydrophobic amino acid residues
Peripheral Membrane Proteins
proteins reversibly associated with either internal/external side of membrane
Ion Channels
can open to allow a specific solute to diffuse (esp. ions). They are either open or closed and open-closed status is often regulated
Transporters
undergo a conformational (shape) change, binding solutes on one side of the membrane and releasing them on the other
Passive Transport
when a solute moves down its concentration gradient spontaneously by diffusion (no energy)
Active Transport/Pumping
using energy in some form (esp. ATP) to move solute against concentration gradient
Facilitated Diffusion
Diffusion using a transporter or channel
Simple Diffusion
just diffusion without anything necessary
Sodium-Potassium Pump
uses energy of ATP hydrolysis to create essential electrochemical gradient in animals cells, pumping Na+ ions out and K+ ions in.
Due to the sodium potassium pump, Na+ is _ _ the cell and K+ Is _ _ the cell
higher outside, higher inside
Coupled Transport
One molecule moves down concentration gradient, releasing energy in a way that drives another molecule to move against concentration gradient (coupled movement)