Unit 2 part 5 Flashcards
Cell Speacialization
Fertilization?
Fusion of gametes
- Leads to development of zygotes
Zygote?
Totipotent stem cell
Totipotent stem cell?
Can develop into all other cell types or into an embryo
- Can produce complete organisms
Blastocyst?
Contains embryonic stem cells
- Zygote develops into blastocyst
Embryonic stem cell?
Are pluripotent
Pluripotent?
Can differentiate into almost all other cell types in organisms but cant complete it
- Can’t produce complete organisms
Cell differentiation?
All cells from a multi cellular organism have some genome
- Stem cells differentiate into specialized cells by expressing some genes and not others
Adult stem cells?
Blastocyst develops into a foetus as embryonic stem cells differentiate into specialized cells
- Some adult stem cells remain to replenish dying cells and repair damaged tissue
- Most adult stem cells are multipotent
Hemotopoietic stem cells
Multipotent b/c they can differentiate into all types of blood cells but not all cells
Development of embryonic cells
They differentiate into specialized cells and tissues in a controlled manner through a group of gene regulating chemicals
Multi potent?
Able to form a range of closely related cells (limited)
Morphogens?
Gene regulating chemicals (transcription factors) that determine the specialized cell that develops according to their concentration
Traits of morphogens?
- produced + released from embryo cells and diffuse through tissues
- They spread, resulting in a concentration gradient across tissue
- Bird to receptors on cells resulting in activation or repression of genes
- Concentration of it determines which gene will be expressed, determining type of specialized cell
Stem cells
Undifferentiated cells that have a limited capacity to divide and can differentiate into specialized cells
- Are self renewal, differentiate, regulate hair growth, and main skin homeostasis
Stem cells niche
Locations in the body where stem cells can be maintained, promoted to proliferate ( rapid self removal), or differentiate
- Adult stem cells are in them
Example of stem cells niche
Bone marrow
- Niche for hemotopoietic stem cells that can differentiate into all types of blood cells
hair follicles
- Contains various pools of stem cells like epithelial, melanocyte, and mesenchymal