Ultimate Treatments Flashcards
Treatment for micro/macroprolactinomas
Cabergoline (dopamine agonist)
Transphenoidal resection
Delirium
Acute:
- haloperidol
- benzodiazepines
Treat underlying cause (infection/ constipation)
Hydronephrosis
Nephrostomy (at renal pelvis)
Sinus bradycardia
Atropine
Pulseless Electrical Activity
Adrenaline
Asystole
Adrenaline
Acute gout
NSAID (Naproxen)
Superficial thrombophlebitis
NSAID (Naproxen)
Topical heparinoids
Compression stockings
LMWH
Cholecystitis
Laparoscopic cholecystectomy
Venous ulcers
Compression stockings
Compression bandages
Skin Grafting
SVC obstruction
Dexamethasone
Balloon venoplasty/ stenting
Radiotherapy/ surgery
Bronchiolitis
Supportive
Asthma (5-16)
SABA (Salbutamol)
+ ICS (Beclomethasone)
+ LTRA (Montelukast)
+ LABA (Salmeterol), stop LTRA (Montelukast)
Asthma (<5)
SABA (Salbutamol)
+ ICS (Beclomethasone)
+ LTRA (Montelukast)
+ Refer to paeds, stop LTRA (Montelukast)
Pyloric stenosis
Ramstedt pyloromyotomy
OCD
1st
- CBT
- Exposure & response prevention
2nd
- SSRI (Sertraline)
3rd
Tricyclic antidepressant
Body dysmorphic disorder
Fluoxetine
SAD
SSRIs
Vit D
Depression
1st
CBT (cognitive behavioural therapy)
2nd
SSRI
3rd
SSRI + CBT
4th
ECT
Mania in BPAD
- Stop antidepressant
- Olanzapine / Haloperidol
Depression in BPAD
CBT + Fluoxetine
GAD
- Self-help + mindfulness
- CBT
- Drugs: - SSRI (Sertraline)
- Alternative SSRI / SNRI
- Pregabalin - Specialist care
Psychosis
Acute: Lorazepam (Benzodiazepines)
Long term: Antipsychotics
PTSD
Watchful waiting CBT Eye-movement desensitisation + reprocessing (EMDR) Drugs: - Venlafaxine (SNRI) - Sertraline (SSRI) - Risperidone (Atypical antipsychotic)
Anorexia
Family behavioural therapy
CBT
Maudsley Anorexia Nervosa Treatment for Adults (MANTRA)
Bulimia
Family behavioural therapy
CBT
Monitor electrolytes
ADHD
- Methylphenidate
- Lisdexamfetamine
- Dexamphetamine
Alcohol withdrawal
- Long acting benzodiazepines
- Chlordiazepoxide
- Diazepam
- Lorazepam (if hepatic failure) - Carbamazepine
Alcohol abstinence
Disulfiram (Antabuse)
- flushing and sick
Acamprostate (Campral)
- reduced cravings
Opioid abstinence
Methadone (opioid mu receptor agonist)
Buprenorphine (mixed opioid agonist/antagonist)
Paracetamol OD
N Acetylcysteine
Activated charcoal if < 1hr since ingestion
Lead poisoning
Dimercaptosucinic acid (DMSA)
Dimercaprol
Calcium edetate
Tricyclic AD OD
IV Sodium bicarbonate
Magnesium sulphate OD
Calcium gluconate
Benzo OD
Flumenazil
Opioid OD
Naloxone
Cocaine OD
Diazepam
Heparin OD
Protamine sulphate
Beta-blocker OD
Atropine + glucagon
Aspirin (salicylate) OD
Alkalisation (IV bicarbonate) = 7.5-8 pH
Haemodialysis
Lithium toxicity
Haemodialysis
Methanol toxicity
Ethanol
Warfarin toxicity
Vit K
Prothrombin complex concentrate
Cyanide OD
Hydroxycoalbumin
Organophosphates (insecticide)
Atropine
Iron OD
Desferrioxamine
Ethylene glycol (anti-freeze) OD
Fomepizole
Ethanol
Haemodialysis
Carbon monoxide poisoning
02 100%
Digoxin toxicity
Digibind
LSD OD
Lorazepam
Local anaesthetic toxicity
IV 20% lipid emulsion
Sleep paralysis
Clonazepam
Narcolepsy
day: modafinil
night: sodium oxybute
Insomnia
Sleep hygiene education + identify causes Short acting benzodiazepines - zopiclone - zolpidem - zaleplon
Fistula in ano
Simple: Keep open (fistulotomy)
Complex: Seton band insertion
Ligation of intersphinteric tract (LIFT)
Fistulas
Self resolving
Varicose veins
Compression stockings
Weight loss
Leg elevation
Severe:
Endothelial ablation
Foam sclerotherapy
Anterior aortic dissection
Surgery + BP control
Posterior aortic dissection
IV Labetalol
AAA
Elective endovascular repair (EVAR)
- via femoral artery
Peripheral arterial disease
Exercise
Statins
Clopidogrel
Surgery
- angioplasty
- stenting
- bypass
- amputation
Neuropathic ulcers
Cushioned shoes
Amputation
Influenza
Vaccine prophylaxis (Autumn)
Oseltamivir
Zanamivir
Constipation
Laxatives
- Bulk forming
- Stimulant (Senna, bisocodyl)
- Osmotic (Lactulose, laid)
- Stool Softeners (sodium docusate)
Alzheimer’s
- Acetylcholinesterase inhibitors
- Donepezil
- Galantamine
- Rivastigmine - NMDA receptor antagonist
- Memantine
Vascular Dementia
- Reduce CVD risk factors
- If mixed with alzheimer’s then treat as such: Acetylcholinesterase inhibitors + NMDA antagonists
Lewy Body Dementia
- Acetylcholinesterase inhibitors
- Donepezil
- Galantamine
- Rivastigmine - NMDA receptor antagonist
- Memantine
NOT HALOPERIDOL
Gardener’s syndrome
Prophylactic colectomy to reduce risk
Neutropenic Sepsis
- Tazocin
- Teicoplanin/ Aztreonam (if Penicillin allergic) - Vancomycin
Tumour lysis syndrome
Calcium gluconate (cardio protection from potassium) Fluids
Bone mets
- Analgesia
- Biphosphonates
- Radiotherapy
Neoplastic spinal cord compression
Oral dexamethasone (high dose)
- reduce oedema
Consider radiotherapy/surgery
Kaposi’s sarcoma
Radiotherapy
Surgical resection
Bladder cancer
CMV
Cisplatin
Methotrexate
Vinblastine
High-grade non-hodgkins lymphoma
R-CHOP
Cyclophosphamide
Hydroxydaunorubicin (doxorubicin)
Vincristine (Oncovin)
Prednisolone
Colorectal cancer
FOLFOX
5-FU
Leucovorin (colonic acid)
Oxaliplatin
Breast cancer
FEC
5-FU
Epirubicin
Cyclophosphamide
Hodgkin’s lymphoma
ABVD
Adriamycin (doxorubicin)
Bleomycin
Vinblastine
Dacarbazine
Retinoblastoma
External beam radiation
Chemo
Photocoagulation
Enucleation
90% survive
Hypokalaemia
IV saline + Potassium (over 4 hours)
Hyperkalaemia
Stabilise cardiac membrane: Calcium gluconate
Short term (shift K from extracellular to intracellular):
Insulin + dextrose infusion
Nebulised salbutamol
Long term (remove K from body)
Calcium resonium
Loop diuretics
Dialysis
Hypocalcaemia
Calcium gluconate
- 10ml of 10% solution over 10mins
Hypercalaemia
- Rehydration (3L per day)
IV 0.9% saline - Biphosphonates
- IV Pamidronate
- Calcitonin salmon
Hypomagnesaemia
IV Magnesium over 24 hours
- can cause diarrhoea
Hypophosphataemia
Phosphate sandoz
Hyperphosphataemia
Bi-phosphonates Calcium acetate (calcium-phosphate binder)
Hyponatraemia
Mild:
Fluid restriction <800ml/day + loop diuretics
Moderate: Hypertonic saline (2.7%) slow infusion
Severe: Bolus hypertonic saline + Vasopressin (ADH receptor agonist)
Hypernatraemia
IV Fluids
SIADH
Fluid restriction
Demeclocycline
ADH Receptor blockers (Tolvaptan)
Malignant hyperthermia (from suxamethonium)
Dantrolene
Motion sickness
Hyoscine
Cyclizine
Promethazine
Neuropathic pain
Acute “rescue”: Tramadol
Chronic: Amitriptyline Duloxetine Gabapentin Pregabalin
Trigeminal neuralgia
Carbamazepine
Post-herpetic neuralgia
Topical capsaicin cream
Analgesia (renal impairment)
- Fentanyl
- Buprenorphine
- Alfentanil
Acute agitation
- Haloperidol
- Chlorpromazine
- Levomepromazine
End of life agitation
Midazolam
End of life hiccups
- Chlorpromazine
2. Haloperidol
End of life secretions
Hyoscine hydrobromide
End of life bowel colic
Hyoscine butylbromide (buscopan)
End of life oral/throat pain
Benzydamine hydrochloride
End of life nausea + vomiting
Levomepromazine
- long acting (8 - 12 hours)
Gastric nausea
Metoclopramide
Extra-pyramidal side effects
Domperidone
Chemotherapy related nausea
Ondansetron
Intra-cranial caused nausea
- Dexamethasone
- reduces oedema around tumours - Cyclizine (for vomiting)
Paroxysmal hemicrania headache
Idomethacin
Cluster headache
Acute:
Triptans
- Sumatriptan
High flow O2
Prophylaxis:
Verapamil
Lithium
Prednisolone
Migraine
Acute:
Triptans (Sumatriptan) + NSAIDs
Metoclopramide
Prochlorperazine
Prophylaxis:
- Topiramate
- Propranolol
- Riboflavin
Menstrual migraine
Fovatriptan
Zolmitriptan
Hydrocephalus
Acute:
External ventricular drain (EVD)
- drains to external bag
Long-term:
Ventriculoperitoneal shunt
- drains to peritoneum