Antibiotics Flashcards

1
Q

3 examples of Macrolides

A

Erythromycin
Clarithromycin
Azithromycin

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2
Q

MoA of macrolides

A

Inhibit bacterial protein synthesis by inhibiting the 50s ribosome subunit

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3
Q

2 examples of quinolones

A

Ciprofloxacin

Levofloxacin

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4
Q

MoA of quinolones

A

Inhibit replication of bacterial DNA by blocking topoisomerase II + IV

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5
Q

Side effects of quinolones

A

Reduce seizure threshold
Tendonitis
Prolong QT

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6
Q

Quinolones are contraindicated in

A

pregnancy and breast feeding

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7
Q

Side effects of Gentamicin

A

Nephrotoxic

Ototoxic

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8
Q

Gentamicin is contraindicated in

A

myasthenia gravis

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9
Q

Example of cephalosporins

A

Ceftriaxone

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10
Q

MoA of cephalosporins

A

Disrupt cell wall synthesis

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11
Q

MoA of penicillins

A

Disrupt cell wall synthesis

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12
Q

MoA of tetracyclines

A

Inhibit 30s subunit, inhibiting protein synthesis

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13
Q

Side effect of Doxycycline

A

Photosensitivity

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14
Q

Side effect of co-amoxiclav

A

Cholestasis

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15
Q

Antibiotic that should be avoided with alcohol

A

Metronidazole

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16
Q

Antibiotic + Glandular fever = rash

A

Amoxicillin

17
Q

3 requirements to prescribe gentamicin

A

Height
Weight
Creatinine