Antibiotics Flashcards
3 examples of Macrolides
Erythromycin
Clarithromycin
Azithromycin
MoA of macrolides
Inhibit bacterial protein synthesis by inhibiting the 50s ribosome subunit
2 examples of quinolones
Ciprofloxacin
Levofloxacin
MoA of quinolones
Inhibit replication of bacterial DNA by blocking topoisomerase II + IV
Side effects of quinolones
Reduce seizure threshold
Tendonitis
Prolong QT
Quinolones are contraindicated in
pregnancy and breast feeding
Side effects of Gentamicin
Nephrotoxic
Ototoxic
Gentamicin is contraindicated in
myasthenia gravis
Example of cephalosporins
Ceftriaxone
MoA of cephalosporins
Disrupt cell wall synthesis
MoA of penicillins
Disrupt cell wall synthesis
MoA of tetracyclines
Inhibit 30s subunit, inhibiting protein synthesis
Side effect of Doxycycline
Photosensitivity
Side effect of co-amoxiclav
Cholestasis
Antibiotic that should be avoided with alcohol
Metronidazole