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The One Deck To Rule Them All > Biochemistry: Miscellanous > Flashcards

Biochemistry: Miscellanous Flashcards

1
Q

Cytokines released by the body in response to viral infections and neoplasia

A

Interferons (IFNs)

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2
Q

There are 3 types of IFNs

A

IFN-Alpha
IFN-Beta
IFN-Gamma

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3
Q

IFN-Alpha and IFN-Beta bind to

A

Type 1 receptors

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4
Q

IFN-Gamma binds to

A

Type 2 receptors

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5
Q

IFN-Alpha is produced by

A

Leucocytes

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6
Q

IFN-Beta is produced by

A

Fibroblasts

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7
Q

IFN-Gamma is produced by

A

Natural killer cells and T helper cells

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8
Q

IFN-Alpha is used for

A 
Antiviral
Hep B
Hep C
Kaposi's sarcoma
RCC metastasis 
Hair cell leukaemia
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9
Q

IFN-Beta is used for

A

Antiviral

MS (reducing exacerbations)

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10
Q

IFN-Gamma is used for

A

Immunomodulation (involving macrophages)
Chronic granulomatous disease
Osteoporosis

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