TZD Flashcards
1
Q
Pioglitazone (g)
A
Actos (b)
2
Q
MOA
A
improves insulin sensitivity in muscle and liver; peroxisome-proliferator-activated receptor gamma agonist
3
Q
common adverse effects
A
edema (swelling)
weight gain
bone fractures
4
Q
rare adverse effects
A
bladder cancer
5
Q
counseling pts.
A
monitor for signs of HF.
may take 6-8 weeks to see full effect.
6
Q
clinical pearls
A
BBW: avoid in pts with HF.
avoid in elderly pts with osteoporosis.
