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Drugs > GLP-1 Agonist > Flashcards

GLP-1 Agonist Flashcards

1
Q

Dulaglutide (g)

A

Trulicity (b)

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1
Q

Liraglutide (g)

A

Victoza (b)

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2
Q

Semaglutide (g)

A

Ozempic, Rybelsus (b)

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3
Q

MOA

A

increases glucose-dependent insulin secretion, decreases inappropriate glucagon secretion, increased B-cell growth/replication, delays gastric emptying, and decreases food intake.

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4
Q

common adverse effects

A

nausea **
diarrhea/vomiting
injection site reactions

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5
Q

rare adverse effects

A

BBW: thyroid cancer

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6
Q

counseling pts

A

GI side effects decrease with time and may return with each dose increase.
rotate injection sites to reduce irritation.
do not reuse needles and dispose safely.

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7
Q

clinical pearls

A

liraglutide (Saxenda) and semaglutide (wegovy) are also used for weight loss.
semaglutide (Rybelsus) comes as an oral tablet.
lower risk of CVD in pts with diabetes.
weekly dosing products available.

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Drugs (39 decks)

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