Sulfonylureas Flashcards
1
Q
Glimepiride (g)
A
Amaryl (b)
2
Q
Glipizide (g)
A
Glucotrol XL (b)
3
Q
MOA
A
stimulates insulin secretion from pancreatic beta cells; continuous squeeze on the pancreas
4
Q
common adverse effects
A
hypoglycemia
weight gain
nausea
photosensitivity **
5
Q
rare adverse effects
A
hepatic toxicity
6
Q
counseling pts.
A
take 30 mins before first meal.
may cause low blood sugar.
may cause hypersensitivity to light
7
Q
clinical pearls
A
really only used when pts cannot afford more effective/well tolerated DM meds.
not contraindicated with sulfa allergy.
lose effectiveness over time.
avoid with G6PD deficiency.
