Proton Pump Inhibitors (PPIs) Flashcards
1
Q
Omeprazole (g)
A
Prilosec (b)
2
Q
Pantoprazole (g)
A
Protonix (b)
3
Q
Esomeprazole (g)
A
Nexium (b)
4
Q
Dexlansoprazole (g)
A
Dexilant (b)
5
Q
MOA
A
blocks the H-K-ATPase which prevents release of stomach acid
takes several days for maximal effectiveness
6
Q
common adverse effects
A
N/V/D
malabsorption of electrolytes and nutrients
7
Q
rare adverse effects
A
osteoporosis and fracture risk
kidney disease
C. diff development
8
Q
counseling pts
A
may take several days for full effect
use these proactively each day; not reactively **
9
Q
clinical pearls
A
may prolong or decrease activity of other drugs
most potent
takes several days for max effectiveness
