Second-Gen Antipsychotics Flashcards
1
Q
Aripiprazole (g)
A
Abilify (b)
2
Q
Clozapine (g)
A
Clozaril (b)
3
Q
Lurasidone (g)
A
Latuda (b)
4
Q
Olanzapine (g)
A
Zyprexa (b)
5
Q
Quetiapine (g)
A
Seroquel (b)
6
Q
Risperidone (g)
A
Risperdal (b)
7
Q
MOA
A
block dopamine-2 and serotonin receptors
8
Q
common adverse effects
A
sedation
weight gain
irregular movements
9
Q
rare adverse effects
A
neuromalignant syndrome (extreme muscle rigidity, hyperthermia, mental status change)
QT prolongation
10
Q
counseling pts
A
smoking reduces levels of clozapine and olanzapine
invega can leave ghost tables in stool
11
Q
clinical pearls
A
clozapine is never used sooner than 3rd line and only prescribed via REMS due to risk for extremely low WBC count
