TCAs Flashcards
1
Q
Amitriptyline (g)
A
Elavil (b d/c)
2
Q
Nortriptyline (g)
A
Pamelor (b)
3
Q
MOA
A
inhibit reuptake of serotonin and NE (also block ACh and histamine receptors –> side effects)
4
Q
common adverse effects
A
orthostasis, tachycardia
weight gain
dry mouth, blurred vision, urinary retention, constipation
major sedation
5
Q
rare adverse effects
A
overdose can cause fatal arrhythmias (QT prolongation)
monitor for suicidal ideation
6
Q
counseling pts
A
takes 1-2 weeks to feel benefit; 6-8 weeks for full effect on mood
take in PM