Thiazides Flashcards
1
Q
Hydrochlorothiazide (generic)
A
Microzide (brand)
1
Q
Chlorthalidone (generic)
A
Thalitone (brand)
2
Q
Metolazone (generic)
A
Zaroxolyn (brand)
3
Q
MOA
A
inhibit sodium reabsorption in distal convoluted tubule, causing increased excretion of Na and Water (lower BP)
4
Q
common adverse effects
A
dizziness
hypotension
headache
electrolyte loss/imbalance
5
Q
counseling pts.
A
take daily, do not double up on doses.
may take with/without food.
6
Q
clinical pearls
A
similar structure to sulfa meds (possible allergy).
chlorthalidone has longer half-life and better CVD protection.
not recommended in pts with severe kidney disease.
