SGLT-2 Inhibitors Flashcards
1
Q
Canagliflozin (g)
A
Invokana (b)
2
Q
Dapagliflozin (g)
A
Farxiga (b)
3
Q
Empagliflozin (g)
A
Jardiance (b)
4
Q
Ertugliflozin (g)
A
Steglatro (b)
5
Q
MOA
A
reduces reabsorption of glucose in the renal tubules, increasing urinary excretion of glucose.
6
Q
common adverse effects
A
increased urination.
UTIs
7
Q
rare adverse effects
A
lower limb amputations (canagliflozin).
hypovolemia/hypotension
bone fractures
8
Q
counseling pts.
A
take with/without food.
take missed doses as soon as you remember, but do not double up on doses.
9
Q
clinical pearls
A
avoid in pts with severe KD.
great benefit in pts with CVD or CKD.
great benefit in pts with HF, with or without diabetes.
