Miscellaneous Antidepressants

Question 1

Mirtazapine (g)

Answer 1

Remeron (b)

Question 2

Trazodone (g)

Answer 2

Desyrel (b)

Question 3

Mirtazapine MOA

Answer 3

TCA with alpha-2 adrenergic antagonistic effect in the CNS, increasing release of serotonin and NE

Question 4

Trazadone (MOA)

Answer 4

inhibits serotonin reuptake and blocks histamine and alpha-1 adrenergic receptors

Question 5

M common adverse effects

Answer 5

weight gain, increased appetite
major sedation
dry mouth, blurred vision, urinary retention, constipation

Question 6

M rare adverse effects

Answer 6

agranulocytosis (life-threatening blood disorder)

Question 7

M counseling pts

Answer 7

takes 1-2 weeks to feel a benefit; 6-8 weeks to feel full effect on mood

Question 8

M clinical pearls

Answer 8

often used in oncology and skilled nursing to help with sleep and appetite stimulation

Question 9

T common adverse effects

Answer 9

major sedation
sexual dysfunction

Question 10

T rare adverse effects

Answer 10

priapism

Question 11

T counseling pts

Answer 11

take in PM

Question 12

T clinical pearls

Answer 12

most often used off-label for sleep