Transplant 4

Question 1

This in a lung transplant biopsy

Answer 1

acute cellular rejection

Question 2

Ischemia-reperfustion injury to lung allograft within 72 hours of transplant

Answer 2

Primary Graft Dysfunction (PGD)

Question 3

Primary graft dysfunction is associated with what type of CLAD?

Answer 3

BOS

Question 4

Tx for BOS

Answer 4

azithro (250 daily x 5 days, then 3x/wk)

Question 5

This in a lung transplant biopsy

Answer 5

CMV (w/ basophilic nuclear inclusion body)

Question 6

Types of infectious pathogens in month 1 post-transplant

Answer 6

hospital-acquired (MRSA, Candida, PsA, GNRs)

Question 7

Types of infectious pathogens in months 2-6 post-transplant

Answer 7

opportunistic (PJP, Listeria, crypto, endemic fungal, KB, HSV-6/7/8, mycobacterial)

Question 8

Types of infectious pathogens in month 1 post-transplant

Answer 8

community-acquired (S. pneumoniae, flu, adenovirus, Rhodococcus, E. coli, S. aureus)

Question 9

This in a lung transplant biopsy

Answer 9

CMV!