Occupational & Environmental Lung Disease 1

Question 1

giant cell interstitial pneumonitis

Answer 1

hard metal lung disease

Question 2

“cannibalistic” multinucleated giant cells in airspaces

Answer 2

hard metal lung disease

Question 3

Duration of exposure to develop silicosis

Answer 3

at least 1 year

Question 4

distribution of fibrosis from asbestosis within lung

Answer 4

basilar and subpleural

Question 5

fibrosis with subpleural curvilinear lines

Answer 5

asbestosis

Question 6

Hut lung is a kind of _____.

Answer 6

pneumoconiosis (anthracosis)

Question 7

Most effective drug for smoking cessation

Answer 7

varenicline (Chantix)

Question 8

loose polypoid plugs of granulation tissue in terminal and respiratory bronchioles, alveolar ducts, and sacs called Masson bodies

Answer 8

COP

Question 9

Leading cause of lung cancer in non-smokers

Answer 9

Radon

Question 10

Dyspnea, patchy hilar infiltrates, and rapid improvement w/ O2 supplementation at altitude >2500 m

Answer 10

HAPE (high altitude pulmonary edema)

Question 11

3 drug options for PPX of HAPE

Answer 11

nifedipine, acetazolamide, dexamethasone

Question 12

Hangover Sx after ascending >2000 m in <24 hrs

Answer 12

acute mountain sickness (AMS)

Question 13

Ataxia, lethargy –> stupor at >3000 m

Answer 13

HACE (high altitude cerebral edema)

Question 14

Tx for HACE

Answer 14

dexamethasone, hyperbaric O2, descent