Transplant 3

Question 1

This in lung transplant biopsy

Answer 1

PTLD (post-transplant lymphoproliferative disorder)

Question 2

initial Tx for post-transplant lymphoproliferative disorder (PTLD)

Answer 2

rituximab & reduced immunosuppression

Question 3

This is in lung transplant biopsy

Answer 3

CMV

Question 4

Infection that is genreally a contraindication to transplant for CF

Answer 4

Burkholderia cenocepacia

Question 5

CF pts should always be referred for transplant if FEV1

Answer 5

30%

Question 6

CF pt should be referred for transplant if FEV1 <40% and markers of shortened survival, such as _____ (4).

Answer 6

6MWT <400m, hypoxia, hypercapnia, or PH

Question 7

CF pts should be referred for lung transplant if FEV1 <40% and complications such as _____ (4).

Answer 7

PTX, massive hemoptysis, BMI <18, or ≥2 exacerbations/year

Question 8

Perihilar infiltrates and/or pleural effusion and lymphocytic vasculitis after lung transplant

Answer 8

acute cellular rejection

Question 9

Tx for acute cellular rejection (ACR)

Answer 9

hi-dose steroids, then taper

Question 10

Allograft dysfunction with donor-specific Abs

Answer 10

antibody-mediated rejection (AMR)

Question 11

Tx for antibody-mediated rejection (AMR)

Answer 11

Rituximab, steroids, IVIg, and plasmapheresis