Obstructive lung disease 1 Flashcards

1
Q

Chest PT has only been proven to improve _____ in bronchiectasis patients.

A

mucus clearance

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2
Q

2 factors predicting highest risk of COPD re-admission

A

depression & prior hospitalization in the past year

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3
Q

Biologic for steroid-dependent asthma independent of IgE, eos, or atopy.

A

Dupilumab

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4
Q

target of dupilumab

A

IL-4

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5
Q

Omalizumab can be prescribed if _____ is elevated.

A

IgE

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6
Q

Mepolizumab can be prescribed if _____ is elevated.

A

eosinophil count

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7
Q

Reslizumab can be prescribed if _____ is elevated.

A

eosinophil count

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8
Q

Target of mepolizumab

A

IL-5

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9
Q

Target of reslizumab

A

IL-5

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10
Q

Target of benralizumab

A

IL-5 receptor (Ben Folds 5)

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11
Q

Dupilumab is also indicated as add-on therapy for non-steroid-dependent asthmatics w/ _____ phenotype.

A

eosinophilic

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12
Q

Which mAbs are indicated for EGPA (3)?

A

omalizumab, mepolizumab, benralizumab

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13
Q

Target of mAbs for EGPA

A

IL-5 –> eos

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