Toxins Ch. 25

Question 1

Anticholinergic toxidrome

Answer 1

dry mouth
mydriasis (dilation)
urinary retention
AMS
Sze
hypoactive BS
hyperthermia
hypertension
muscle twitching
respiratory depression
widened QRS
heart block 
mad as a hatter, hot as hell, red as a beat, dry as a bone, and blind as a bat

Question 2

Anticholinergic treatment

Answer 2

activated charcoal, sodium bicarb, lido/mag, benzos

Question 3

SSRI OD treatment

Answer 3

ciproheptadine, also Dantrolene for muscle relaxation

Question 4

Carbon monoxide poisoning S/SX

Answer 4

Ha. red flushed skin, AMS, vomiting

Question 5

Carbon monoxide TX

Answer 5

high flow O2,

Question 6

Cyanide treatment

Answer 6

hydroxycobalamin, sodium thiosulfate, amyl nitrate, sodium nitrate

Question 7

Causes of cyanide poisoning

Answer 7

inhaled smoke from burning plastics

Question 8

Signs of tricyclic antidepressant OD?

Answer 8

Anticholinergic toxidrome

Question 9

Treatments for tricyclic antidepressant OD

Answer 9

1. Sodium Bicarb to alkalize urine and to treat
   dysrhythmias
2. Lido or mag for ventricular arrhythmia
3. benzos for seizure

Question 10

Treatment for sympathomimetic OD

Answer 10

1. benzos

2. Sodium Bicarb

Question 11

What drug should be avoided in serotonin syndrome?

Answer 11

Haloperidol, it can worsen hyperthermia p.283

Question 12

What is neuroleptic malignant syndrome?

Answer 12

A response to antipsychotic meds
usually occurs more than 24 hours after med initiation
Results in severe muscle rigidity, hyperthermia, AMS, autonomic instability,

Question 13

Meds that may cause NMS?

Answer 13

Haldol, reglan, phenergan, droperidol

Question 14

Treatments for NMS?

Answer 14

dantrolene, bromocriptine, benzos, sodium bicarb, fluids