Chp. 23 Oncology Flashcards
Several consequences of B- Thalasemmia
hepatomegaly, splenomegaly chronic hepatitis
2 types of supportive care for B Thalasemmia
folic acid, deferoxamine for elevated iron
Two treatments for hemophilia
Aminocropoic acid, DDAVP (desmopressin) to promote actor VIII release
VWB disease causes of aquired
wilms tumor, lupus, hypothyroidism, valporic acid, cipro
Most common cause of death in sickle cell diseases
Acute chest syndrome p. 258
Age range for splenic sequestration
< 5 yo
Most common cancers in kids under 14
leukemia, nervous system , lymphoma, sarcoma, renal p. 258
TLS onset time frame
w/in 7 days of chemo
How does TLS affect the kidneys
hyperuricemia may cause uric acids to crystallize in the tubules leading to ARF.
High phosphorus in TLS may cause what symptoms
N/V, neuro symptoms like lethargy and seizures
High calcium in TLS may lead to
constipation, nausea, vomiting, bone pain, tetany,
What is hyperluekocytosis?
Seen in leukemia where WBCs exceed 100,00/mm3 and increase viscosity while clogging capillaries compromising end organ perfusion
