Chp. 23 Oncology Flashcards

1
Q

Several consequences of B- Thalasemmia

A

hepatomegaly, splenomegaly chronic hepatitis

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2
Q

2 types of supportive care for B Thalasemmia

A

folic acid, deferoxamine for elevated iron

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3
Q

Two treatments for hemophilia

A

Aminocropoic acid, DDAVP (desmopressin) to promote actor VIII release

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4
Q

VWB disease causes of aquired

A

wilms tumor, lupus, hypothyroidism, valporic acid, cipro

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5
Q

Most common cause of death in sickle cell diseases

A

Acute chest syndrome p. 258

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6
Q

Age range for splenic sequestration

A

< 5 yo

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7
Q

Most common cancers in kids under 14

A

leukemia, nervous system , lymphoma, sarcoma, renal p. 258

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8
Q

TLS onset time frame

A

w/in 7 days of chemo

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9
Q

How does TLS affect the kidneys

A

hyperuricemia may cause uric acids to crystallize in the tubules leading to ARF.

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10
Q

High phosphorus in TLS may cause what symptoms

A

N/V, neuro symptoms like lethargy and seizures

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11
Q

High calcium in TLS may lead to

A

constipation, nausea, vomiting, bone pain, tetany,

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12
Q

What is hyperluekocytosis?

A

Seen in leukemia where WBCs exceed 100,00/mm3 and increase viscosity while clogging capillaries compromising end organ perfusion

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