Toxicology Flashcards
acute arsenic poisoning, acute mercury poisoning, chronic severe lead poisoning
SE: hypertension
dimercaprol
pica, ingestion of flakes of paint, abdominal colic, acute encephalopathy, wrist drop, mental retardation
lead
chronic lead poisoning (oral treatment), for mild to moderate cases
SE: GI disturbance
succimer
chronic severe lead poisoning, for acute symptomatic cases
SE: hypocalcemia, renal toxicity
EDTA
rice-water stools, garlicky breath, Mee’s lines, raindrop pigmentation, milk and roses complexion
arsenic
hemorrhagic gastroenteritis, renal failure, loosening of gums and teeth, erethism
inorganic mercury
Minamata disease (cerebral palsy, deafness, blindness, mental retardation)
organic mercury
severe GI necrosis, hemosiderosis, restrictive cardiomyopathy
iron
acute iron poisoning, hemochromatosis
deferoxamine
hepatotoxicity, Kayser-Fleischer rings, sunflower cataracts
copper
Copper poisoning, Wilson’s disease
SE: drug-induced lupus
penicillamine
Antidote for benzodiazepine toxicity
Flumazenil
Antidote for iron poisoning (vomiting, abdominal pain, bloody diarrhea)
Deferoxamine
Antidote for lead poisoning
EDTA
Antidote for copper poisoning
Penicillamine