Anti-Asthma Drugs

Question 1

DOC for acute asthma attacks

Answer 1

SABA
salbutamol
albuterol

Question 2

adjunct for asthma maintenance

Answer 2

LABA
“-terol”
salmeterol

Question 3

prophylaxis for nocturnal asthma
SE: seizures
antidote: propranolol

Answer 3

theophylline
aminophylline
pentoxifylline
doxotylline

*pentoxyphylline- used for intermittent claudification

Question 4

bronchodilator of choice in COPD and in patients with heart disease

Answer 4

“-ium”
ipratropium
tiotropium
glycorronium

Question 5

stabilizes mast cells, prevents calcium influx, no bronchodilator effect

Answer 5

cromolyn

Question 6

DOC for asthma maintenance

SE: oral candidiasis, growth stunting

Answer 6

fluticasone
beclamethasone
budesonidemometasone
ciclesonide

*for status asthmaticus - use IV prednisone or hydrocortisone

Question 7

lipoxygenase inhibitor; used for exercise, antigen and aspirin induced bronchospasm
SE: increase AST/ALT (hepatotoxicity)

Answer 7

zileuton

Question 8

blocks receptors of slow-reacting substances of anaphylaxis (leukotrienes C4, D4, E4)

SE: Churg-Strauss syndrome (rare) - a small and medium sized vessel inflammation

Answer 8

montelukast

Question 9

anti-IgE antibody

very expensive and only administered IV

Answer 9

omalizumab

Question 10

A leukotriene synthesis inhibitor that can cause increase in hepatic enzymes and altered liver function

Answer 10

Zileuton