Toxicology Flashcards
Poison
Any substance that impairs health or causes death by its chemical action when it enters the body or come in contact with skin
Toxicology
Study of toxins, antidotes, and the effects of toxins on the body
Antidote
Substance that will neutralize or counteract the effects of poison
Common Antidotes
- Naloxone = Narcotic OD
- Oxygen = Carbon Monoxide poisoning
- Atropine 2 Pam Chloride = Pesticide/ Nerve gas exposure
Ingestion
- Drug/ substance swallowed/ absorbed into GI tract/ small intestine
- Slow onset
- Most common
- Find out what they took, how much, when and their weight
Ingestion SxSx
- Swelling or burns around the mouth
- Nausea/ vomiting/ diarrhea
- ALOC
- Abdominal pain
- Others, depending on drug
What does Activated Charcoal do?
Trade names:
- Actidose, Actidose- aqua
Actions:
- Binds to poisons in the stomach, not allowing them to be get absorbed in the blood stream
Activated Charcoal Side effects
- Black stools
- Vomiting
- Repeat dose if patient vomits
Activated Charcoal Indications and Contradictions
Indications:
- Ingestion
- Within one hour of ingestion
Contradictions
- Inability to swallow
- ALOC
- Acids or alkalis (bleach, ethyl alcohol)
- Cyanide
Activated Charcoal Dose
- 1gm/ kg
- Adults: 30- 100g
- Children: 12.5- 25g
Inhalation
- Breathing in a poison
- Rapid onset
Inhalation SxSx
- Dyspnea
- Chest pain
- Airway or breathing sounds (Stridor, Hoarseness, Coughing, Wheezing, Crackles)
- Neurological issues (Dizzy, Headache, ALOC,, Seizures)
What is Injection and some examples?
- Injected under the skin, into a muscle, or directly into a blood stream
- Bites and stings
- Drugs
Injections SxSx
- Injection site swelling
- Euphoria
- Nausea/ vomiting
- Weakness/ Fever/ Chills
What is Absorption?
- Poison enters through skin or mucous membranes
- Plant or chemicals
Absorption SxSx
- Liquid or powders on skin
- Burns/ blisters
- Rash
- Itching/ redness/ swelling
What is Carbon Monoxide poisoning and examples?
- Colorless, tasteless, odorless gas
- Binds to RBC at a much higher affinity than hemoglobin, so hemoglobin cannot bind
- Causes: incomplete combustion (furnaces, water heaters, gas stove, fire places, car exhausts)