ToRCHeS

Question 1

<p>Toxoplasma</p>

Answer 1

<p>Maternal: usually asymptomatic, rarely lymphadenopathy; Neonatal triad: Chroioretinits, hydrocephalus, intracranial calcifications</p>

Question 2

<p>Rubella</p>

Answer 2

<p>Maternal: Arthritis, lymphadenopathy, rash; Neonatal triad: PDA (or pul. aa hypoplasia), cataracts, deafness (also may have "blueberry rash from thrombocytopenia)</p>

Question 3

<p>CMV</p>

Answer 3

<p>Maternal: Mono-like sxr (fever & lymphadenopathy); Neonatal: Unilateral hearing loss, seizures, petichial rash, "blueberry muffin" rash</p>

Question 4

<p>HIV</p>

Answer 4

<p>Maternal: Variable depending on CD4 count; Neonatal: recurrent infections, chronic diarrhea; Prevent vertical transmission wit: Zidovudine, HAART, C-section</p>

Question 5

<p>HSV-2</p>

Answer 5

<p>Maternal: usually asymptomatic; Neonatal: Temporal encephalitis, herpetic vesicular lesions; Definitely need C-section if active herpetic lesions</p>

Question 6

<p>Syphilis</p>

Answer 6

<p>Maternal: Primary and secondary are 2 stages likely to result in fetal infection; Neonatal early s/s: HSM, hemolytic anemia, jaundice, rash w/ desquamation of hands/feet, snuffles (blood tinged nasal secretions), radiographica changes @ birth (metaphyseala dystrophy and periostitis); Neonatal Late s/s: Hutchinson teeth (notching of incisors), saddle nose, frontal bossing, saber shins, CN8 deafness</p>

Question 7

Maternal PKU

Answer 7

Infant: microcephaly, mental retardation, growth retardation, congenital heart defects