Antidotes Flashcards
Acetaminophen
N-acetylcysteine (replenishes glutathione)
Salicylates
NaHCO3 (alkalinize urine), dialysis
Amphetamines (basic)
NH4Cl (acidify urine)
Acetylcholinesterase inhibitors, organophosphates
Atropine with pralidoxime
Anti-muscarinic, anti-cholinergic agents
Physostigmine salicylate, control hyperthermia
B-blockers
Glucagon
Digitalis
normalize K+, Lidocaine, Anti-digoxin Fab fragments, Mg2+ (KLAM)
Iron
Deferoxamine, deferasirox
Lead
CaEDTA, dimercaprol, succimer, penicillamine
Mercury, arsenic, gold
Dimercaprol (BAL), succimer
Copper, arsenic, gold
Penicillamine
Cyanide
Nitrite (to release cyanide) + thiosulfate (to bind the cyanide) then give methylene blue to return Hb back from methemoglbin; hydroxocobalamin
Methemoglobin
Methylene blue, vitamin C
Carbon monoxide
100% O2, hyperbaric O2
Methanol, ethylene glycol (antifreeze)
Fomepizole>ehtanol, dialysis