Antidotes Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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1
Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

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1
Q

Amphetamines (basic)

A

NH4Cl (acidify urine)

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1
Q

Acetylcholinesterase inhibitors, organophosphates

A

Atropine with pralidoxime

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1
Q

Anti-muscarinic, anti-cholinergic agents

A

Physostigmine salicylate, control hyperthermia

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1
Q

B-blockers

A

Glucagon

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1
Q

Digitalis

A

normalize K+, Lidocaine, Anti-digoxin Fab fragments, Mg2+ (KLAM)

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2
Q

Iron

A

Deferoxamine, deferasirox

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3
Q

Lead

A

CaEDTA, dimercaprol, succimer, penicillamine

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4
Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

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5
Q

Copper, arsenic, gold

A

Penicillamine

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6
Q

Cyanide

A

Nitrite (to release cyanide) + thiosulfate (to bind the cyanide) then give methylene blue to return Hb back from methemoglbin; hydroxocobalamin

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7
Q

Methemoglobin

A

Methylene blue, vitamin C

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8
Q

Carbon monoxide

A

100% O2, hyperbaric O2

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9
Q

Methanol, ethylene glycol (antifreeze)

A

Fomepizole>ehtanol, dialysis

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10
Q

Opioids

A

Naloxone/Naltrexone

11
Q

Benzodiazepines

A

Flumazenil

12
Q

TCAs

A

NaHCO3 (plasma alkalinization)

13
Q

Heprin

A

Protamine

14
Q

Warfarin

A

Vitamin K, Fresh frozen plasma

15
Q

tPA, streptokinase, urokinase

A

Aminocaproic acid (inhibit plasminogen activation, which inhibits fibrinolysis)

16
Q

Theophylline

A

B-blocker

17
Q

Serotonin syndrome

A

Cyproheptadine

18
Q

Rat poison

A

Fresh Frozen Plasma and Vitamin K1