Topic A4 - Haemostasis and shock Flashcards
What is haemostasis?
It is the bodys natural response to stop a bleeding
(The body forms a temporary plug to seal an injury)
⭢ To accomplish that, platelets that circulate in your blood stick to the damaged tissue and activate. That activation means they can “recruit” more platelets to form a platelet “plug” to stop blood loss from the damaged area
Name the different events of haemostasis:
Primary haemostasis
Secondary haemostasis
Thrombus dissolution
What happens during primary haemostasis?
Your body forms a temporary plug to seal an injury.
To accomplish that, platelets that circulate in your blood stick to the damaged tissue and activate. That activation means they can “recruit” more platelets to form a platelet “plug” to stop blood loss from the damaged area. That clot works much like a cork or bottle stopper, keeping blood in and debris or germs out. Primary hemostasis may also involve constriction (narrowing) of the damaged blood vessel, which can happen because of substances that activated platelets release.
What happens during secondary haemostasis?
It stabilizes the plug,
This step, sometimes called coagulation, involves molecules in your blood called “coagulation factors.” Those factors activate in sequence, the “coagulation cascade,” which amplifies clotting effects as the sequence continues. Ultimately, the coagulation cascade forms a substance called fibrin. During this step, the platelet plug acts like bricks and the fibrin acts like mortar. Together, they form a solid, stable clot.
What happens during thrombus dissolution?
Your body remodels the existing clot into a fibrin clot. Your body does that because blood clots are a temporary patch, not a permanent solution. That removal involves a process called fibrinolysis. During fibrinolysis, your body remodels the clot into the same kind of tissue that was there before the injury
Name the different disturbances of the circulation:
Pre hemostasis = Decreased blood flow
Hemostasis = Blood flow is stopped
Post hemostasis = Start of the blood flow
Peristasis = Slow blood flow
Name a mild case of circulatory disturbance:
Collapse
It is mild and lasts for a short time
What is shock?
is a state of circulatory failure that happens when the organs and body tissues do not receive enough blood flow to support their oxygen and metabolic demands, putting them at risk of hypoxia and cellular injury.
Name the different types of shock:
- Cardiogenic
- Hypovolemic
- Blood maldistribution
- Septic shock
What is cardiogenic shock?
From acute of chronic heart failure
What is hypovolemic shock?
From blood or fluid loss
What is blood maldistribution shock?
From sepsis, anaphylactic shock or it might be neurogenic
What is septic shock?
It is a life-threatening condition caused by an infection in the bloodstream (sepsis or blood poisoning) in which blood pressure falls dangerously low and many organs malfunction because of inadequate blood flow
Name the phases of shock:
- Non-progressive/compensated shock
- Decompensated/progressive shock
- Irreversible shock.
Non-progressive/Compensated shock
The normal circulatory compensatory mechanisms eventually cause full recovery without help from outside therapy.