Topic A2 – Local hyperaemia Flashcards

1
Q

What is hyperaemia?

A

an excess of blood in the vessels supplying an organ or other part of the body

To understand hyperaemia we need to understand the circulatory system, composed of: heart, blood, vessels and microcirculation

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2
Q

What is local hyperaemia?

A

The body adjust the blood flow to meet the metabolic needs of different tissues

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3
Q

What is the terminal part of the circulatory system?

A

The microcirculation

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4
Q

What is the microcirculation?

A

Circulation of the smallest blood vessels.

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5
Q

What are the factors which regulates the blood flow?

A
  1. Hydrodynamic factors
  2. Neurohormonal regulation
  3. Vasomotion control
  4. Terminal circulatory bed
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6
Q

What is the terminal circulatory bed?

A

They allows for the exchange of water, carbon dioxide, oxygen, and nutrients, as well as to eliminate waste. It is a network of microcirculation to transport cellular and fluid material to the surrounding organ system

This is also where the circulatory disturbances happens

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7
Q

Explain the cardiovascular system:

A
  1. Large and small blood vessels are used to transport oxygen and nutrient supply.
  2. When the blood reaches the capillaries, the microcirculation, the nutrient and wastes can be exchanged.
  3. The capillaries are grouped together in capillary beds, which is the place where it is all exchanged.
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8
Q

Name the different types of circulatory disturbances

A

Local: Hyperaemia and ischaemia
General: Collapse and shock

Collapse = mild form ⭢ Shock = life threatening

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9
Q

Where can we see the local hyperamiea?

A

In both veins and arteries

Veins = Local and systemic congestion
Arteries = Active hyperaemia

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10
Q

Types of hyperaemia:

A

Hyperaemia due to increased blood flow = active hyperaemia
Hyperaemia due to decreased blood flow

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11
Q

What is hyperaemia due to increased blood flow?

A

Happens when an organ is being used.
The organ will utilize the blood, and another organ will therefore have less blood.
The vessels widen to increase the blood flow

Example: When eating, the GI-tract uses the blood and there will be less in the brain and we get tired

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12
Q

What is hyperaemia due to decreased blood flow?

A

Happens following the active hyperaemia.
The muscles will contract, but there will be blood still in the given area and the influx is decreased. When the speed of the blood flow is decreased, the vascular permeability is increased and the blood will go through the wall of the vessels.

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13
Q

What happens after a hyperaemia due to decreased blood flow?

A

We get pre hemostasis = Speef of the blood flow is decreased.
then there is an Extravasation of RBC and WBC

Extravasation = leaking of blood into the tissue around

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14
Q

Pathology of hyperaemia:

A

often we can only see PM lesions in the living animals, often with vascular injections

The area is swollen, warm and has a bluish-red colour

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15
Q

What is vascular injections?

A

superficial blood vessels that normally are hidden, will now be visible.

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16
Q

What is local congestion?

A

A passive process which happens in the terminal circulatory bed.
The vein is obstructed or compressed, leading to trombosis and/or torsion of the intestines

17
Q

Pathology of local congestion

A

Organs can be seen as dark red colour and a large amount of blood on the cut surface. On the membrane we see dark red colour, and often there is serous fluid in the lumen of the organs. We can also see INFARCERATIO

18
Q

What is the different between infarction and infarct

A

Infarct = Area of ischemic necrosis

Infarction = the process that leads to the ischemic necrosis

19
Q

What is systemic congestion?

A

It is associated with increased circulatory time due to cardiac pumping inefficiency ⭢ heart failure, shock

Can appear in all organs