A18 - Fibrinous inflammation

Question 1

What is fibrinois inflammation?

Answer 1

a form of inflammation which is characterised by fibrin deposition. It may be acute, but more often it is a chronic response. It results from the exudation of a high concentration of the plasma protein fraction

The exudate is rich in fibrinogen

Starts out as a serous inflammation

Question 2

Where can we see fibrinous inflammation?

Answer 2

Seorus membrane
Mucous membrane
Organs - But ONLY in lungs = called croupous penumonia

Question 3

Outcome of fibrinous inflammation on the serous surface

Answer 3

Starts as a cloudy precipitation. After 5-6 days we get organisation and the granulation tissue goes from the subserosa, causing villous growth. Later on we can get adhesion between the serous membranes, calling it extensive thickening or connective tissue ligaments

Question 4

Outcome of fibrinous inflammation on the mucousal surface

Answer 4

There are two types of inflammation:

1. Croupus
2. Diphteroid

Question 5

What is croupous inflammation?

Answer 5

It is superficial.
There will be loose fibrin coagulates on the membrane, and if the fibrin is removed we get a fast regeneration.

Question 6

What is diptheroid inflammation?

Answer 6

It is a deep inflammation. Can be both diffused and circumscribed

Outcome: Deep = coagulative necrosis
Profound = Superficial healing and organisation

Question 7

Outcome of fibrinous inflammation in the lungs

Answer 7

If the exudate percipitates in the alveolar acinin, the ducts and in the micro bronchi ⭢ the fibrin will accumulate and destroy the alveolar epithelial cells, which will detach

Oedema can be seen as mottled in the surround interstitium and there will be no ventilation

Question 8

What happens during fibrinous inflammation of the lungs?

Answer 8

There are 3 stages:

1. Congestion, hyperaemia and fibrinogen leaks from the blood vessels

2. Hepatisation = The neutrophils are mainly induced, containts 3 small stages

2a. Red = Red blood cells is also present
2b. Grey = Most visible cell is the neutrophils
2c. Yellow = After undergone fat degradation, removal of fibrin

3. Lysis = Healing takes place

Question 9

Pathology of fibrinous inflammation of the lungs:

Answer 9

The lungs keep is shape, but they are enlarged with a mottled colour. There is no sound of crepitation, because there is no bubbles/air