A17 - Suppurative inflammation Flashcards
What is a suppurative inflammation?
It is an acute inflammation caused by pyogenic bacteria, chemicals or necrotic tissue. The tissue repsonse consists of fluid with high concentration of protein, high numbers of leukocytes
where can the suppurative inflammation be seen?
Can occur on mucous membrane, serous membrane and inside organs
suppurative inflammation inside the organs
Have 3 different forms:
1. Phlegmone = Diffuse purulent inflammation Widely spread, not localized or confined. Usually seen in the connective tissue
2. Abscess = Localised purulent inflammation. Circumscribed form IConfined to a limited area
3. Microabcess = Seen on histopathology only. Tiny absvesses filled with pus
Outcome of the suppurative inflammation on the mucous membrane
Three outcomes:
1. Pyorrhea = The mucous membrane has an orifice, so the pus will drain ⭢ It will heal quite nicely
2. Empyema = The pus will accumulate
Accumulation in the uterus = Pyometra
3. Can develop to a chronic purulent inflammation
Outcome of the suppurative inflammation on the serous membrane
We can see circulatory disturbances = Vascular injections or haemorrhages.
On the serous membrane, we call the inflammation according to the area it is located
1. Pericardium = Pyopericardium
2. Thorax = Pyothorax
3. Joints = Pyoarthros
What is an abscess?
A collection of pus in a cavity formed by tissue that have been broken down by infectious bacteria.
They occur when the acute inflammation fails to eliminate the stimulus
Pus = contains exudative, inflammation cells and debris
What are the zones of an abscess?
they have different zones, which nornally wont be seen, because theyre all mixed.
Inner nucler is the Pathogen, which is sorrounded by the exudate. The next layer is the Neutrophil granulocytes, then we have a layer of histiocytes and lymphocytes, with a layer of granulation tissue and finally the outer layer is the Capsule
Exudate layer and neutrophil granulocytes are alwasy mixed togheter
