Topic 14: Animal Skeletal and Muscular Systems Flashcards
attach bones to bones (joints)
Ligaments
attach bones to muscle
dense connective tissue
Tendons
(torso) bones such as skull, backbone, ribcage, breastbone, vertebral column
Axial skeleton
attached to axial at pectoral girdle or pelvic girdle [hips and shoulders]
Appendicular skeleton
Bone function is
calcium and phosphate reservoir
not modeled in cartilage first
Flat bones
modeled in cartilage first
blood cells made in the bone marrow of this type of bone
Long bones
located in spaces of spongy bone
Bone marrow
Structure of bone
collagen fibers coated in hydroxyapatite crystals (calcium phosphate)
weak and flexible part of bone; redistributes stress to help hydroxyapatite crystals from fracturing
Collagen matrix
secrete collagen fibers
Osteoblast (cells)
calcified collagen fibers
Osteocytes
encase osteocytes
Lacunae
narrow channels that run parallel to length of the bone
interconnect and carry blood vessels and nerve fibers
surrounded by lamellae bone layers
Halversian canals
thin, concentric layers of bone surrounding Halversian canals
Lamellae
openings in bone between osteocytes and the canals
Canaliculi
cartilage at ends of bones, involved in joints
Articular cartilage
can dissolve bone, allowing remodeling
Osteoclasts
nearly immovable joints, joined by connective tissue (fontanels in infants) (ex. cranial bones)
Sutures
sutures in human infants
fontanels
freely movable joints
Synvovial joints
fibrous structure containing ends of bones, strengthened by ligaments
Synvovial capsule
degeneration of connective tissue in synvovial joint
Rheumatoid arthritis
part of tendon that attaches to stationary base
Muscle origin
part of tendon that attaches to movable bone
Muscle insertion
tendons that decrease joint angle, move bones closer
Flexors
tendons that increase joint angle, move bones further apart
Extensors
muscle type with long, spindle-shaped, mononuclear cells
Smooth muscle
muscle type with slow, maintained contraction with minimal energy use
Smooth muscle
muscle type with very long, parallel multinucleate cells (muscle fibers)
Skeletal muscle
muscle type with rapid contraction with large force
Skeletal muscle
muscle type with striated, mononuclear branching cells
Cardiac muscle
separate cardiac muscle cells
Intercalated disc
Myofilament structure
long chains of actin and myosin proteins (also troponin and tropomyosin)
(muscle) polymer in thin filaments (2 strings wound in loose double helix)
Actin
(muscle) spontaneous polymerization in thicker filaments
10x longer than actin
twisted pair of polypeptides
Myosin
dark bands of stacked thick (myosin) filaments
A bands
light bands of stacked thin (actin) filaments
I bands
dark lines of dense material in the center of I bands; form anchors for thin filaments
Z lines
lighter region in center of A band, where thin filaments are not present
H bands
mechanism of contraction
Sliding filament
Mechanism of contraction:
myosin “pulls” ______ in, reducing size of ____ and _____
myosin “pulls” actin in, reducing size of H bands and I bands
organizational muscle unit of Z-I-A-H-A-I-Z
Sarcomere
myosin heads (ATPases) “cock” heads and bind with actin to form cross-bridges
power stroke
myosin head binds to new ATP and releases from actin
Cross-bridge cycle in muscle contraction
myosin head changes shape and pulls actin toward sarcomere center
Power stroke
formed where nerve fiber embeds in muscle
Neuromuscular junction
released by motor neuron at neuromuscular junction
stimulates electrochemical impulse that travels along muscle fiber membrane and opens Ca++ channels
Acetylcholine
stimulated by acetylcholine; travels along muscle fiber membrane, opening Ca++ channels
Electrochemical impulse
opened by electrochemical impulse caused by acetylcholine
located on muscle membranes; embedded in SR
Ca++ channels
have Ca++ channels embedded in it
Sarcoplasmic reticulum (SR
SR wraps around myofibril
calcium pump actively transports Ca++ into SR, flooding its sarcoplasm
Ca++ and troponin move tropomyosin out of the way so myosin binds to actin
Effect of opening Ca++ channels
located in SR, flooded with Ca++ when calcium channels open
Sarcoplasm
bound to tropomyosin
this in addition to Ca++ move tropomyosin out of the way so myosin binds to actin
Troponin
When does contraction end?
Ca++ pumped back into SR
Ca++ is responsible for this
Excitation-contraction coupling
covers myosin binding site on actin in resting muscle
Tropomyosin
repetitive firing of motor neuron
increased stimulation rate (increased [Ca++], increased total contraction force, and smooth, forceful (individual) contractions)
Summation
Summation increases the rate of stimulation, which leads to these effects
increased [Ca++]
increased total contraction force
smooth, forceful (individual) contractions
In summation, ______ must be faster than individual ________
Neuron firing frequency must be faster than individual muscle twitch
how fast muscle will contract and relax
Twitch
maximum contraction value (smooth, sustained)
Tetanus
multiple, larger motor units are activated to increase contraction force
Recruitment
innervates many muscle fibers (or motor units)
Motor neuron
set of muscle fibers controlled by one neuron
Motor unit
initiates impulse in cardiac muscle
Pacemaker
Cardiac muscle have no ______ or ______
summation or tetanus
2 myocardias in the heart: one for _____ and _____
One for 2 atria (receive blood)
One for 2 ventricles (pump blood to lungs and body)
Characteristics of smooth muscle contraction:
Not organized in sarcomeres
Myosin molecules attached to dense bodies or muscle membrane
No SR
Effects of no SR in smooth muscle contraction
Ca++ comes from extracellular space
Ca++ channels opened by automatic neurotransmitter activation
Ca++ binds to calmodulin, which activates MLCK to phosphorylate myosin heads and activate them
Ca++ in sarcoplasm binds to this, which then activates MLCK
Calmodulin
phosphorylates myosin heads, activating them; activated by Ca++/calmodulin combination
Myosin light chain kinase (MLCK)
slightly movable
bones bridged entirely
by cartilage
Cartilaginous joints
Vertebral bones are an example of ____ joints
cartilaginous joints