TIVH subtypes

Question 1

TIVaH?

Answer 1

macrophages

Question 2

TIVbH?

Answer 2

eosinophils

Question 3

TIVcH?

Answer 3

cytotoxic T cells

Question 4

TIVdH?

Answer 4

neutrophils

Question 5

macrophages

Answer 5

TIVaH

Question 6

eosinophils

Answer 6

TIVbH

Question 7

cytotoxic T cells

Answer 7

TIVcH

Question 8

neutrophils

Answer 8

TIVdH

Question 9

antigens are recognized by Th1 cells which secrete IL-2 and IFN-gamma which activates Tc and macrophages (also some IL-17 secreted by Th17 cells which recruit neutrophils).

what type IV H reaction is this?

Answer 9

TIVHa

Question 10

what mediates TIVHa?

Answer 10

Th1 and Th 17

Question 11

mantoux/ppd test, granulomatous lesions, contact dermatitis – poison ivy, nickel, latex gloves, gluten, rheumatoid arthritis, multiple sclerosis, psoriasis, etc.

what type IV H reaction is this?

Answer 11

TIVHa

Question 12

later cellular phase of type I hypersensitivity can be classified here.

Answer 12

TIVHb

Question 13

more of a cytotoxic T cell reaction than macrophages or other inflammatory cells.

Answer 13

TIVHc

Question 14

Th17 lymphocytes secrete IL-17 which recruits neutrophils.

Answer 14

TIVHd

Question 15

how long does T4H take?

Answer 15

2-3 days, hence delayed, then visible response after exposure, induration, due to memory cells