Overview in defense against microbes 1 Flashcards

lecture 26-27

1
Q

microbes does the immune system respond to?

A

bacteria, extracellular/intracellular (facultative/obligatory)
fungi, extracellular/intracellular
viruses
parasites, protozoan(unicellular)intracellular/extracellular and metazoan(multicellular)
tumors or malignant cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what immune cells respond to extracellular pathogens?

A

CD4+ T cell response and humoral immune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what immune cells response to intracellular pathogens?

A

CD8+ T cell response, CD4+ TH1 response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what immune cells respond to metazoan parasites?

A

Th2 type response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

this is a field of immunology which results in an immune response against the microbe rather than the microbe itself; collateral damage

A

immunopathology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

outline the immune response steps?

A
breach in barrier
entry of pathogen
initial inflammation
recognition of PAMPs by PRRs of innate immune cells, innate immune cells active
cytokines/chemokines
recruitment of inflammatory cells
inflammation 
activation of APCs
different cytokine mileau
adaptive immune response
control of infection
How well did you know this?
1
Not at all
2
3
4
5
Perfectly