Immune Evasion by Viruses Flashcards
check on learning
1
Q
example of antigenic variation?
A
influenza, rhinovirus, HIV
2
Q
example of inhibition of antigen processing
blockade of TAP transporter
removal of class I molecules from the ER
A
HSV
CMV
3
Q
production of decoy MHC molecules to inhibit NK cells
A
CMV (murine)
4
Q
production of cytokine receptor homologues
A
Vaccina, poxvirus, CMV(chemokine)
5
Q
production of immunosuppressive cytokine
A
EBV (IL-10)
6
Q
infection and death or functional impairment of immune cells
A
HIV
7
Q
inhibition of complement activation
recruitment of factor H
incorporation of CD59 in viral envelope
A
HIV
HIV, vaccinia, human CMV
8
Q
inhibition of innate immunity
inhibition of access to RIG-I RNA sensor
inhibition of PKR (signaling by IFN receptor)
A
vaccinia, HIV
HIV, HCV, HSV, polio
