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Haem > thrombotic thrombocytopenic purpura > Flashcards

thrombotic thrombocytopenic purpura Flashcards

1
Q

what is it a type of?

A

microangiopathy

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2
Q

what is a microangiopathy?

A

when microthrombi (platelets) form and occlude microvasculature

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3
Q

what is TTP due to?

A

acquired antibodies against the enzyme which cleaves VWF

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4
Q

how do patients usually present?

A

fever
fluctuating CNS
impaired renal function
thrombocytopenia
neuro affects - confusion, headaches

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5
Q

what will be seen on blood smear?

A

schistocytes

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6
Q

what is the management?

A

plasma exchange therapy

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Haem (30 decks)

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