Thrombosis Flashcards
Platelets bind to exposed
collagen
endothelial cell injury lead to platelet a_____
aggregation
Platelet aggregation is the first stage of t____ f______
thrombus formation
What feedback loops are present?
Positive feedback loops (platelets being sticky lead to more platelets being sticky, fibrinogen converting to fibrin)
What is a thrombosis?
Solid mass of blood constituents formed within intact vascular system during life
What can cause a thrombosis?
Change in vessel wall, change in blood flow, change in blood constituents
Aspirin inhibits p_______ a_______
platelet aggregation
Covid increases the l___ production of clotting factors
liver’s
F________ levels in a severely ill covid-19patient are 10–14 g/l compared with 2-4g/l normally
Fibrinogen
What is an embolus?
Mass of material in the vascular system able to become lodged within a vessel and block it
What is ischaemia?
Reduction in blood flow
What is infarction?
Reduction in blood flow with subsequent death of cells
End artery supply is where
One organ is supplied by only one artery
Where in the body is supplied by more than one artery?
Lungs, liver, some parts of the brain