thiazide diuretics Flashcards
1
Q
how do thiazide diuretics work?
A
work by inhibiting sodium reabsorption at the beginning of the distal tubule (DCT) by blocking the thiazide-sensitive Na-Cl- symporter.
2
Q
common adverse effects of thiazide diuretics
A
dehydration postural hypotension hyponatraemia, hypokalaemia, hypocalcaemia gout impaired glucose tolerance impotence
3
Q
rare adverse effects of thiazide diuretics
A
thrombocytopaenia
agranulocytosis
photosensitivity rash
pancreatitis
