ACE inhibitors Flashcards
1
Q
What are ACE inhibitors used for?
A
younger patients with hypertension.
heart failure.
diabetic rephropathy.
role in the secondary prevention of ischaemic heart disease.
2
Q
mechanism of action for ACE inhibitors
A
Inhibit the conversion angiotensin I to angiotensin II.
ACE inhibitors are activated by phase 1 metabolism in the liver.
3
Q
side effects of ACE-inhibitors
A
cough
angioedema
hypokalaemia
first-dose hypertension
4
Q
cautions and contradictions
A
pregnancy and breastfeeding
renovascular disease
aortic stenosis
hereditory of idiopathic angioedema
